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Application of the Nanotrap Technology Platform for Immunome Biomarker Preservation and Monitoring

Award Information
Agency: Department of Defense
Branch: Defense Advanced Research Projects Agency
Contract: W911NF-16-C-0060
Agency Tracking Number: D2-1563
Amount: $1,728,113.82
Phase: Phase II
Program: SBIR
Solicitation Topic Code: SB112-005
Solicitation Number: 2011.2
Solicitation Year: 2016
Award Year: 2016
Award Start Date (Proposal Award Date): 2016-04-27
Award End Date (Contract End Date): 2018-02-02
Small Business Information
9385 Discovery Blvd.
Manassas, VA 20109
United States
DUNS: 011762701
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Ben Lepene
 (800) 615-0418
Business Contact
 Mr. Ross Dunlap
Phone: (800) 615-0418
Research Institution

Immune marker panel tests can provide significant information for understanding and addressing many areas of health and wellness and disease conditions. However, conducting large clinical studies to identify the significance of panel based biomarkers has been hampered primarily by the logistics of acquiring quality samples from clinical subjects and extracting and measuring the valuable markers on the downstream analytical platforms.Additionally, the transition from clinical study to clinical test has been hampered by the lack of consistent technologies and methodologies used for both settings. The Nanotrap technology can address both of these requirements.Ceres Nanosciences proposes to develop a technology platform to address the need for both improved sample collection methods, extraction protocols and improved downstream detection limits (>100-fold improvement) of low-abundance and highly labile cytokines as part of an immunome panel. A baseline immunome study will be completed using the developed technology to assess immunome biomarker levels in healthy patients over a one year period.

* Information listed above is at the time of submission. *

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