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ZeroG TRIP Training Responses in Postural Rehabilitation

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43AG059257-01
Agency Tracking Number: R43AG059257
Amount: $224,717.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NIA
Solicitation Number: PA16-302
Solicitation Year: 2016
Award Year: 2017
Award Start Date (Proposal Award Date): 2017-09-15
Award End Date (Contract End Date): 2019-08-31
Small Business Information
21720 RED RUM DR STE 187
Ashburn, VA 20147-5882
United States
DUNS: 825904738
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (571) 292-8889
Business Contact
Phone: (571) 292-8889
Research Institution

Project Summary
The goal of this project is to significantly enhance our understanding and treatment of inadequate balance
responses in the elderly and in patients with neurological impairments following external perturbations such as
a slip or trip Our laboratory studies have shown that balance responses can be improved with practice in the
elderly and in patients with Parkinsonandapos s disease PD However these laboratory studies have not been
translated into clinical practice because there is currently no safe and reliable technology for training and
quantifying balance responses particularly during overground walking The ZeroG gait and balance training
system developed and now commercialized by Aretech LLC Ashburn VA allows individuals with gait and
balance disorders to safety practice walking overground with concurrent body weight support and fall
protection The current system does not allow patients to practice recovering from unexpected external
perturbation for balance training nor does the system contain the necessary instrumentation for quantifying
balance responses
In this Phase I SBIR we will significantly enhance the capabilities of the ZeroG system by developing
controlled balance perturbations of adjustable magnitude and direction that can be delivered during standing
and overground walking The framework for the ZeroG balance perturbation sequences called TRIP Train
Responses in Postural Rehabilitation will be based upon the scientific findings of our laboratory over the last
decade We will develop the specific perturbation characteristics needed to train postural stepping responses
in people with balance deficits due to PD and work closely with physical therapists on usability and safety
Finally we will determine the feasibility and clinical usability of the ZeroG TRIP system through questionnaire
feedback from patients and therapists
Phase II of this SBIR will focus on additional technical development of the ZeroG TRIP system and subsequent
clinical testing of the device Specifically we plan to develop and test innovative metrics of postural stepping
responses for ZeroG TRIP using the body worn sensors with the partnership between Aretech LLC and
APDM Inc We will also utilize the APDM sensors to track the patientandapos s movements throughout the gait cycle
so that we can automatically trigger the TRIP perturbation rather than having to manually trigger the
perturbation Finally we will refine the user interfaces on both the touch screen computer and wireless tablet
making the controls intuitive for the user yet providing sufficient flexibility to control the perturbation sequences
The clinical testing during Phase II will focus on comparing improvements in balance responses and balance
confidence after training with TRIP compared to ZeroG body weight support walking in people with PD
The ZeroG TRIP system will enable physical therapists to safely and systematically assess and treat
inadequate balance responses which are a major contributor to falls disability and declining quality of life Project Narrative
Falls and subsequent fall related injuries are a common and disabling result of aging and is exacerbated in
individuals with neurological disorders The ZeroG TRIP system that will be developed in this project will
enable physical therapists to safely and systematically assess and treat inadequate balance responses which
are a major contributor to falls disability and declining quality of life

* Information listed above is at the time of submission. *

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