You are here

Developing a Clostridium molecular toolkit for bioconversion of food waste

Award Information
Agency: Department of Defense
Branch: Army
Contract: W911NF-17-P-59
Agency Tracking Number: A17A-011-0051
Amount: $149,999.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: A17A-T011
Solicitation Number: 2017.0
Solicitation Year: 2017
Award Year: 2017
Award Start Date (Proposal Award Date): 2017-07-17
Award End Date (Contract End Date): 2018-01-31
Small Business Information
953 Indiana St
San Francisco, CA 94107
United States
DUNS: 079761816
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Zachary Sun
 CEO / Co-founder, Synvitrobio, Inc.
 (646) 725-6686
Business Contact
 Zachary Sun
Phone: (646) 725-6686
Research Institution
 Northwestern University
 Zachary Sun
633 Clark St
Evanston, CA 60208
United States

 (646) 275-6686
 Nonprofit College or University

Waste generation at forward bases creates significant challenges; its disposal presents an economic cost with no direct benefit and its accumulation or burning is a health hazard. The bioconversion of waste into useful compounds could save thousands annually for every soldier and tens of millions in capital expenditure. However, widespread adoption is impeded by low conversion efficiency. We propose developing a Clostridium molecular toolkit, composed of a Clostridium cell-free system and associated parts (functional enzymes and regulatory regions), that can be used to engineer Clostridium to conduct efficient food waste fermentation. Synvitrobio and its academic subcontractor have extensive experience building E. coli cell-free prototyping systems, and believes an opportunity exists to build Clostridium cell-free systems. At the end of Phase I, we will de-risk the feasibility of the toolkit, and identify higher-order compounds to develop. In Phase II, we will mature the Clostridium cell-free toolkit for commercial deployment, and demonstrate the use of engineered Clostridium strains to convert food waste to high-value chemicals.

* Information listed above is at the time of submission. *

US Flag An Official Website of the United States Government