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Insightful Surgical Vision Technology (ISVision) for intelligent real-time display of anatomic, physiologic, and pathologic information in surgery

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41EB026402-01A1
Agency Tracking Number: R41EB026402
Amount: $242,769.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NIBIB
Solicitation Number: PA17-303
Solicitation Year: 2017
Award Year: 2018
Award Start Date (Proposal Award Date): 2018-09-13
Award End Date (Contract End Date): 2019-08-31
Small Business Information
Boston, MA 02127-1533
United States
DUNS: 079855777
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (617) 258-5184
Business Contact
Phone: (617) 258-5184
Research Institution
WASHINGTON, DC 20010-2916
United States

 Domestic Nonprofit Research Organization

Intelligent intraoperative display of anatomic and physiologic information coupled to real time situational
awareness to critical tissues will benefit all surgeryThe current surgical vision is limited to naked human eyes
in open surgery or more recently using laparoscopic digital imaging for minimally invasive surgery and robot
assisted surgeryIn laparoscopic visionalthough the visualization of surface anatomy and tissue physiology in
the surgical field of view has been enhanced by recent advances in optical imaging technologythe imaging
paradigm still remains passive and still poses a significant challenge due to the inherent narrow peripheral vision
and limited depth perceptionWe propose the next generation laparoscopic vision system that provides intelligent
display of unrecognized tissue structures to human eyesOur proposed use of a new paradigm and surgical
vision technologycalled ISVisionTMequipped with modular plenopticD Color HD camera and snapshot NIR
hyperspectral imagerwill permit a clear visualization of the critical target tissue of interestsurrounding anatomy
into the operative fieldand situational awareness for both the tool and tissue to the surgeonOur Phase I effort
comprises of engineering the clinically viable ISVision platform and testing the performance of its intraoperative
useSpecificallythe ISVision system will clearly and precisely identify different tissue characteristicsaccurately displaying physiologic information including tissue perfusion and blood flowFollowing the
Phasewe anticipate undertaking a Phase II projectduring which we will develop a clinical grade ISVision
system and investigate its performance and utility in the operating roomWhile the initial focus of the Phase I
and II effort is on the complex surgery such as liver resection due to crucial nature of critical sub surface
structures located underneath liver hilum and parenchymathe ISVision system will potentially play an enabling
role in all surgeries and establish it as a vital component of the operating room of the future

* Information listed above is at the time of submission. *

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