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Biologically-Derived Targeted Antimicrobials for Textile Applications

Award Information
Agency: Department of Defense
Branch: Army
Contract: W911NF-18-C-0068
Agency Tracking Number: A2-7196
Amount: $999,968.00
Phase: Phase II
Program: STTR
Solicitation Topic Code: A14A-T012
Solicitation Number: 2014.0
Solicitation Year: 2014
Award Year: 2018
Award Start Date (Proposal Award Date): 2018-09-27
Award End Date (Contract End Date): 2020-09-27
Small Business Information
89 Rumford Avenue
Newton, MA 02466
United States
DUNS: 066594979
HUBZone Owned: No
Woman Owned: Yes
Socially and Economically Disadvantaged: No
Principal Investigator
 Avni Argun, Ph.D.
 (781) 528-0581
Business Contact
 Cortney Mittelsteadt, Ph,D.
Phone: (781) 529-0529
Research Institution
 Texas A&M University
 Heather Knee
400 Harvey Mitchel Pkwy South Suite 300, 3578 TAMUS
College Station, TX 77845
United States

 (979) 845-4788
 Nonprofit College or University

Antimicrobial treatment of military textile systems is intended to provide enhanced protection to the Warfighter in the field by preventing colonization of harmful bacteria that cause various skin and soft tissue infections (SSTI) such as impetigo, boils, abscesses, cellulitis and life-threatening necrotizing fasciitis. Current treatments can impart antimicrobial functionality to textiles; however, they all possess broad-spectrum antimicrobial activity, affecting all skin bacteria. The processing of these compounds is also costly with high environmental impact. Bio-derived antimicrobial coatings offer selective elimination of targeted bacteria without affecting commensal bacteria required for skin health. There is considerable interest in using phages, the viruses of bacteria, to control pathogenic bacterial populations. They can uniquely offer specificity against targeted bacteria. By judicious selection of phages and host coating matrices, this program aims to develop robust antimicrobial coatings with high efficacy and specificity against S. aureus. The focus of the work is the validation of coating efficacy and demonstration of high-volume production at low costs.

* Information listed above is at the time of submission. *

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