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Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point ofCare Applications
Phone: (256) 679-8660
Phone: (256) 783-4506
Contact: Catherine Bigger, Ph.D.
Phone: (205) 581-2142
Type: Domestic nonprofit research organization
GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we plan tocontinue our device maturation by integrating automated sample preparation into the disposable cartridge, modifying the fluid path foroptimal target acquisition, expanding the Febrile Illness panel and progressing the commercialization of the product. The goal of this Topic is aportable pathogen detection system for undifferentiated febrile illnesses for use in far-forward environments by the Warfighter. Thepathogens of interest for this Phase II effort include Influenza, Dengue, Chikungunya, Lassa Fever, and Crimean-Congo Hemorrhagic Feverviruses, and the bacteria Yersinia pestis, Rickettsia typhi, Francisella tularensis and Burkholderia species. The assay will also differentiatesamples containing bacterial agents from those containing fungal or viral pathogens.
* Information listed above is at the time of submission. *