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Developing Software for Pharmacodynamics and Bioassay Studies
Award Information
Agency: Department of Defense
Branch: Defense Health Agency
Contract: W81XWH-17-C-0153
Agency Tracking Number: H16C-001-0003
Amount:
$149,935.00
Phase:
Phase I
Program:
STTR
Solicitation Topic Code:
DHP16C-001
Solicitation Number:
2016.0
Timeline
Solicitation Year:
2017
Award Year:
2017
Award Start Date (Proposal Award Date):
2017-09-11
Award End Date (Contract End Date):
2018-04-10
Small Business Information
7926 Jones Branch Drive,
mclean, VA
22102
United States
DUNS:
001899546
HUBZone Owned:
No
Woman Owned:
No
Socially and Economically Disadvantaged:
No
Principal Investigator
Name: Hua Liang
Phone: (202) 994-7844
Email: hlaing@gwu.edu
Phone: (202) 994-7844
Email: hlaing@gwu.edu
Business Contact
Name: Larry Liu
Phone: (703) 910-3400
Email: larry.liu@tconnex.com
Phone: (703) 910-3400
Email: larry.liu@tconnex.com
Research Institution
Name: The George Washington University
Contact: Tapan Nayak
Address:
Phone: (202) 994-6549
Type: Nonprofit College or University
Contact: Tapan Nayak
Address:
2121 I Street, NW
Array
Washington/, DC
20052
United States
Phone: (202) 994-6549
Type: Nonprofit College or University
Abstract
Estimation of the primary parameters like IC 50 in traditional dose-response modelsmay fail or lead to misleading results when the observations are non-onotonic due to drugresistance or virus mutation in various biomedical lab research. The objective of this project isto develop a novel approach to assess dose response relationship, which is applicable to generalpharmacologic, toxicologic, or other biomedical studies that exhibit a non-monotonic dose-response relationship, and to develop inference tools. User-friendly software, that can handleboth monotonic and non-monotonic dose-response relationships, will be developed and availableto the scientific community.
* Information listed above is at the time of submission. *
