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Nano-synthetic Materials Smart System Enabling Sensor Discovery and Fabrication



OBJECTIVE: Develop a smart system of the rapid discovery, development, and evaluation of nano-synthetic detecting materials as sensors for Synthetic Tissue, Organ, Nerve and Skin (STONeS). These discovered novel sensor materials will be used to fabricate new detectors that demonstrate “murmuration behavior” that record properly/improperly performed emergent procedures, useful in medical simulation training with additional potential utility seen in forward medical operational environments. 

DESCRIPTION: Applying appropriate STONeS sensors into mannequins or part-task trainers to provide feedback signals can mimic close-to-real-life response, ensuring surgical procedural accuracy and improving training efficiency and fidelity for military medical service members. STONeS sensor enabled part-task trainers will increase training availability and accessibility, while decreasing overall training cost. Demand for the application of nanosensors in medical simulation training is rising as nanotechnology-enabled sensors to provide a faster, more accurate and sensitive detection, and therefore it enables new solutions in physical, chemical, and biological sensing STONeS applications. The diversity of nanosensor technologies and applications requires a broad diversity of nanomaterials. However, ideal sensing materials to satisfy the capability gaps remaining in civilian and military medical simulation have yet to be revealed in practice. To accelerate this sensor development, DHA considers R&D efforts in autonomous detection to enable the broad, application-driven discover of nano-synthetic material to be both necessary and urgent. Currently there is no similar effort available to provide an effective solution. The goal of this topic is to create a nanomaterial synthetic platform with innovative methodology strategies to quickly discover novel nanomaterials as sensor materials to develop nanosensors fit for at least one of the following STONeS capabilities: • Detection of touch • Detection of pressure • Detection of stretch • Detection of disruption and closure • Monitoring temperature • Monitoring gases • Monitoring humidity • Monitoring liquids • Monitoring radiation. 

PHASE I: A feasibility study that demonstrates the scientific, technical, and commercial merit of the methodology. Identify and define the right approaches to establish a high throughput automatic nanomaterial synthetic and screening platform to rapidly discover appropriate STONeS sensing materials. Required Phase I deliverables will include: • Prove deep understanding and review of current nano-synthetic sensing material applications in STONeS. • Develop a methodology to enable high throughput nanomaterial synthetic system. • Develop approaches for application-driven discovery for sensing material for STONeS properties and targets. • Provide proof of concept data and support the technical feasibility. • Prove the proposed technology has advantages over the current technologies in use. 

PHASE II: Phase II effort will culminate in a well-defined deliverable prototype based upon the Phase I proof of concept work, with an expectation of comprehensive development, detailed demonstration, and final validation. The prototyped high throughput platform should be utilized to produce at least two novel discoveries of nanomaterials. The characteristics of the new STONeS nanomaterials are expected to have some of the following features: • Printable • Flexible and/or Stretchable • Scalable • Unobtrusive • Reliable • Inexpensive • Wireless • Low-voltage and/or self-power Required Phase II deliverables: • Produce prototype hardware and software based upon Phase I work. • Develop, test and validate the prototyped high throughput nano-synthetic material platform. • Provide a detailed plan for nano-synthetic material discovery procedures. • Provide practical implementation for nano-synthetic material discovery. • Develop processes, select appropriate applications and demonstrate at least two productions as novel discoveries of nanosensing materials for STONeS applications. 

PHASE III: Phase III work will be a continued R&D effort with the potential to transition to the advanced developer or the genesis of an advanced manufacturing capability. It’s expected to be a novel nanosensors development using Phase II discovered nanomaterials. All sensors developed will improve the use of STONeS in medical simulation training with important military and commercial impact. It can also have the potential to become an important large nano-synthetic sensing material database/library commercially available to significantly accelerate the sensor discovery and development. The discovery and fabrication of these new sensors will be benefit in both training and operational environment such prolong field care, telemedicine, and the future autonomous systems. 


1: Meital Segev-Bar, et al., A Tunable Touch Sensor and Combined Sensing Platform: Toward nanoparticle-based Electronic Skin. ACS Applied Materials & Interfaces. 2013

KEYWORDS: Nanotechnology, Nanosynthetic Material, Sensor 

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