The Food and Agriculture Organization (FAO) of the United Nations predicts that feeding the world’s growing population will require a doubling of global food production by 2050. Fulfilling this need will require new technologies to improve both productivity and efficiency of food animals. The Animal Production and Protection topic area aims to develop innovative, marketable technologies that will provide significant benefit to the production and protection of agricultural animals. New technologies for rapid detection, point-of-care, treatment, and prevention of disease are needed to improve productivity and enhance the biosecurity of our herds and flocks. Better technologies are also needed to develop and enhance alternatives to the use of antibiotics since pathogen resistance and human sensitivity to residue food products derived from animals have become of increasing concern. To meet increasing consumer demand for value-added animal products, innovative technologies are needed to address the challenges presented by non-conventional management systems and strategies. In addition, there is an urgent need for technologies that decrease the impact of animal agriculture on the environment and optimize use of our natural resources. Technological advances in animal production and protection will not only enhance the safety of the Nation’s food supply and contribute to environmental stewardship, they will also allow American producers to remain competitive in the global marketplace and contribute to global food security.