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Secure Homomorphically Encrypted National Registry of COVID-19 Recovered Plasma Donors

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41HG010978-01
Agency Tracking Number: R41HG010978
Amount: $565,671.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: 172
Solicitation Number: PA18-591
Timeline
Solicitation Year: 2018
Award Year: 2019
Award Start Date (Proposal Award Date): 2019-09-09
Award End Date (Contract End Date): 2021-08-31
Small Business Information
7919 AVENIDA KIRJAH
La Jolla, CA 92037-3507
United States
DUNS: 080795543
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 AZIZ BOXWALA
 (617) 294-9269
 aziz.boxwala@elimu.io
Business Contact
 AZIZ BOXWALA
Phone: (617) 294-9269
Email: aziz.boxwala@elimu.io
Research Institution
 UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
 
7000 FANNIN STREET, UCT 1000
HOUSTON, TX 77030-5400
United States

 Nonprofit College or University
Abstract

PROJECT SUMMARY
Treatment with convalescent plasma (CP) was recently approved by the FDA for seriously ill patients of
COVID-19. There are many institutions and hospitals that have implemented CP programs, but they all face
the challenge of finding sufficient and appropriate donors. The constraints of matching, imbalances in supply
and demand, and privacy concerns pose several challenges to engage donors. Considering multiple
stakeholders (patients, donors, hospitals), we will develop new algorithms based on multikey homomorphic
encryption to protect the privacy of patients and donors, with additional functionality to simplify the registration
process, and conduct optimization for plasma donation (of patients who recovered from COVID-19). We are
dedicated to the public good and will make freely available the code / resources developed within the
framework of this project. If we succeed, our project will build a secure national registry for potential plasma
donors and may save many lives.Narrative
We are proposing a novel platform for convalescent plasma donation with integrated privacy protection and
resource optimization. The goal is to remove the barriers and concerns for COVID-19 recovered patients to
donate their plasma to save severely ill patients. This supplement grant extends our parent project with
innovative homomorphic encryption model and a customized design to meet this urgent need.

* Information listed above is at the time of submission. *

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