The SHARKS Program seeks to develop new designs for economically attractive Hydrokinetic Turbines (HKT) for tidal and riverine currents. Tidal and riverine energy resources are renewable, have the advantage of being highly reliable and predictable, and are often co-located with demand centers, while HKT devices can be designed with low visual profiles and minimal environmental impact. These energy-producing devices are also uniquely suited for micro-grid applications, supplying energy to remote communities and other “blue economy” or utility-scale applications. This Program is aimed at applying Control Co-Design (CCD), Co-Design (CD) and Designing-for-OpEx (DFO) methodologies to HKT design. These three design methodologies require the concurrent (rather than sequential) application of a wide range of disciplines, starting at the conceptual design stage. The technical challenges that inhibit the development of highly efficient HKT designs are mutually dependent, and require expertise from a range of scientific and engineering fields for optimization. These codependent technical challenges make HKT design a perfect candidate for CCD, CD and DFO, and will necessitate the formation of multi-disciplinary teams to resolve their inherently coupled design considerations.