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Spatial Genomics for in situ single cell expression analysis in the brain

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 2R44MH115538-03
Agency Tracking Number: R44MH115538
Amount: $1,989,076.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: 101
Solicitation Number: PA19-272
Solicitation Year: 2019
Award Year: 2020
Award Start Date (Proposal Award Date): 2020-09-04
Award End Date (Contract End Date): 2022-08-31
Small Business Information
Pasadena, CA 91107-5211
United States
DUNS: 080426411
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (626) 460-8095
Business Contact
Phone: (626) 460-8095
Research Institution

Spatial Genomics, Inc. is commercializing seqFISH technology that can visualize thousands of
genes at the mRNA level in single cells with spatial information preserved. Recent advances now
make it possible to achieve 10,000 gene multiplexing in single cells directly in tissues (Eng et al.,
Nature 2019). With this technology, novel cell types can be discovered in situ and spatial
organizations can be directly identified and visualized in brain tissue sections.NARRATIVE
Spatial Genomics is developing a transformative technology to profile the transcriptome in single
cells in situ. This technology can image gene expression directly in the brain and has many
applications to neurodegenerative diseases.

* Information listed above is at the time of submission. *

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