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Intracranial Pressure Assessment and Screening System for Viral or Bacterial Infections (IPASS-VBI)

Award Information
Agency: Department of Defense
Branch: Office for Chemical and Biological Defense
Contract: W911QY-20-P-0072
Agency Tracking Number: C192-005-0021
Amount: $167,487.62
Phase: Phase I
Program: SBIR
Solicitation Topic Code: CBD192-005
Solicitation Number: 19.2
Solicitation Year: 2019
Award Year: 2020
Award Start Date (Proposal Award Date): 2020-02-03
Award End Date (Contract End Date): 2020-10-30
Small Business Information
175 Great Road
Bedford, MA 01730
United States
DUNS: 078513593
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Michele Pierro
 Senior Signal Processing and Algorithm Engineer
 (781) 373-1930
Business Contact
 Stephen Mattox
Phone: (781) 373-1930
Research Institution

Vivonics is proposing a novel approach to address the needs of a non-invasive and real-time system to measure intracranial pressure (ICP) to support development of medical countermeasures. The proposed Intracranial Pressure Assessment and Screening System for Viral or Bacterial Infections (IPASS-VBI) leverages Vivonics expertise in non-invasively assessing ICP in humans due to traumatic brain injuries (TBI) by means of non-invasive optical-based technologies. The proposed system is based on our ongoing development of an ICP monitor (IPASS), which uses non-invasive estimates of ICP ranges, for medics and clinicians to screen and monitor ICP changes and fluctuations in time. The proposed IPASS-VBI is based on non-invasive near-infrared (NIR) measurements, which allows for a fast and easy assessment of ICP changes. Unique among the various approaches to non-invasive ICP measurement currently under development, the IPASS-VBI requires only two body-surface mounted sensors (typically located on the ear lobe and forehead) to provide continuous readings from a portable device. The IPASS-VBI system will be designed and engineered to be easy to use and provide reliable and real-time readings of ICP changes.

* Information listed above is at the time of submission. *

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