NASA Missions and Programs create a wealth of scientific data and information that are essential to understanding our earth, our solar system, and the universe. Advancements in information technology will allow many people within and beyond the Agency to more effectively analyze and apply these data and information to create knowledge. For example, modeling and simulation are being used more pervasively throughout NASA, for both engineering and science pursuits, than ever before. These tools allow high-fidelity simulations of systems in environments that are difficult or impossible to create on Earth, allow the removal of humans from experiments in dangerous situations, provide visualizations of datasets that are extremely large and complicated, and aid in the design of systems and missions. In many of these situations, the assimilation of real data into a highly sophisticated physics model is needed. Information technology is also being used to allow better access to scientific data, more effective and robust tools for analyzing and manipulating data, and better methods for collaboration between scientists or other interested parties. The desired end result is to see that NASA data and science information are used to generate the maximum possible impact on the nation: to advance scientific knowledge and technological capabilities, to inspire and motivate the nation's students and teachers, and to engage and educate the public.