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Improved Performance, Stable Artificial Oxygen Carrier for Battlefield Casualty Care

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-04-C-0117
Agency Tracking Number: A045-024-0154
Amount: $99,986.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: A04-T024
Solicitation Number: N/A
Solicitation Year: 2004
Award Year: 2004
Award Start Date (Proposal Award Date): 2004-06-16
Award End Date (Contract End Date): 2005-02-22
Small Business Information
350 Second Ave.
Waltham, MA 02451
United States
DUNS: 019677178
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Vladimir Gilman
 Senior Scientist
 (781) 684-4174
Business Contact
 Richard Wiesman
Title: Executive Vice President
Phone: (781) 684-4242
Research Institution
 University of Pittsburgh
 Marina Kameneva
McGowan Institute , University of Pittsburgh
Pittsburgh, PA 15260
United States

 (412) 383-9458
 Nonprofit College or University

Abstract: Foster-Miller and the University of Pittsburgh propose to develop a new artificial oxygen carrier (OC) formulation with improved stability and tissue oxygenation performance for use in first echelon combat casualty care applications. In Phase I, they will demonstrate the feasibility of using structure-property relationships and computer-aided property prediction methods to develop improved perfluorocarbon (PFC) emulsions that are stable over extended periods of time (more than one year) under the widely varying storage conditions expected in battlefield use. In addition, they will demonstrate the feasibility of obtaining improved tissue oxygenation using the University of Pittsburgh's innovative drag reducing polymer (DRP) additive. The feasibility demonstration will include measurements of emulsion particle size and stability under a range of conditions (including freeze/thaw stability), oxygen carrying capability of the OC formulation, in vitro rheology measurements, and preliminary assessments of the effect of OC formulation on various blood parameters. (P-040435)

* Information listed above is at the time of submission. *

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