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Microfluidic Array Biosensor

Award Information
Agency: Department of Defense
Branch: Office for Chemical and Biological Defense
Contract: N00014-03-M-0403
Agency Tracking Number: C031-0139
Amount: $69,996.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2003
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
Photonic Systems Division, 20600 Gramercy Place Bl
Torrance, CA 90501
United States
DUNS: 125297759
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Gregory Zeltser
 Senior Scientist
 (310) 530-7892
Business Contact
 Gordon Drew
Title: Chief Financial Officer
Phone: (310) 320-3088
Research Institution

In response to CBD need, Physical Optics Corporation (POC) proposes to develop and fabricate a novel Microfluidic Array Biosensor (MICAB) as a new, sensitive, simple-to-use, hybrid instrument system for the early and rapid detection of environmentalbacterial and viral pathogens. The concept of the system is based on the combination of microfluidics and evanescent wave phenomena. The MICAB will consist of three elements: a 3D capillary array, a backlit diffuser screen, and a processing/analyzingsubsystem. The device will significantly enhance the operational efficiency and readiness of shipboard, land-based, and expeditionary naval forces. In Phase I, POC will demonstrate the feasibility of the MICAB device for rapid and extremely sensitivedetection of pathogens in liquid. Phase II development will culminate in fabrication and validation of MICAB system incorporating an array of molecular markers (100 and more) for rapid and reliable detection of multiple food and water pathogens byuntrained personnel. The successful completion of this project will result in a sensitive, reliable, easy-to-use and cost-efficient food and water pathogen detection device. Other potential applications include food industry; medical diagnostics ofpathogens as well as immunoassay for hormones, medications, and metabolites; wastewater treatment facilities; pharmaceutical industries; and environmental monitoring and industrial safety.

* Information listed above is at the time of submission. *

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