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Compact Integrated System for Quantifying Inhaler Dose Concentration

Award Information
Agency: Department of Commerce
Branch: National Institute of Standards and Technology
Contract: N/A
Agency Tracking Number: 09-306-36
Amount: $89,995.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2009
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
20 New England Business Center
Andover, MA 01810
United States
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Krishnan Parameswaran
 (978) 689-0003
Business Contact
Phone: () -
Research Institution

Aerosol delivery of pharmaceuticals is an effective means of treating numerous diseases. Proper administration of drugs in this form requires knowledge of the droplet size and concentration of the active pharmaceutical ingredient (API) within the aerosol. Optical imaging is a robust method for obtaining this information. Physical Sciences Incorporated proposes to develop, build, and test a novel measurement system including optical patternation that will monitor droplet size and API concentration produced by metered dose inhalers. The development program will enhance the NIST prototype system by adding optical patternation software capable of quantifying the API concentration using fluorescence intensity measurements and correlating droplet fluorescence and scattering images. The resulting system will provide a robust, cost-effective measurement solution for qualifying commercial inhaler use with new drug formulations.

* Information listed above is at the time of submission. *

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