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Wearable Electrophysiologic Sensor Suite for Detection of Neurotoxic Effects

Award Information
Agency: Department of Defense
Branch: Army
Contract: DAAD1903C0101
Agency Tracking Number: A033-0169
Amount: $99,946.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 2003
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
5764 Pacific Center Blvd, Suite 107
San Diego, CA 92121
United States
DUNS: 016541711
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Robert Mtthews
 Principal Investigator
 (858) 373-0832
Business Contact
 Alexis Bugaj
Title: Operations Manager
Phone: (858) 200-1949
Research Institution
 John Polich
10550 North Torrey Pines Road
La Jolla, CA 92037
United States

 (858) 784-8176
 Nonprofit College or University

This program combines a breakthrough in electrophysiologic sensors with state-of-the-art (SoA) research into the determination of cognitive state and autonomic arousal. The sensor breakthrough enables accurate measurement of bioelectric signals withoutcontact to the skin, even operating through clothing if desired. The target configuration for the prototype system to be built in Phase II is a small array of the new bioelectrodes mounted on the outer surface of a lightweight cap, or off-the head on theinside of a helmet..In Phase I measurements will be performed at the Cognitive Electrophysiology Laboratory (CEL) at the Scripps Research Institute, in order to define a set of measurement channels that can be used as the inputs to a cognitive gauge. This gauge will combinethe physiologic inputs using SoA algorithms and insights, to produce a single reading indicative of impending cognitive dysfunction. The measurements will use low levels of alcohol intake to affect cognitive performance under protocols developed at CELover the last five years.In Phase II a functional prototype including the sensor array and all algorithms will be demonstrated. The prototype will be tested for extended periods and under different conditions on a statistically significant number of subjects at CEL. The proposed system will provide a dramatic improvement in capability to monitor the cognitive state. By measuring brain function directly, the system will be able to detect effects due to neurotoxins, uncompensated stress, sleep loss, and informationoverload. Other military applications could include alertness monitoring, and as a component of future man machine interfaces. Significant commercial opportunities exist in the research market transitioning to medical applications such asneuropharmacology, and civilian security applications such as fire departments and hazardous waste treatment.

* Information listed above is at the time of submission. *

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