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LINKING TECHNOLOGY AND PRESERVED MEMORIES FOR DEMENTIA

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: PHS2001-2
Agency Tracking Number: 2R42AG014292-02A1
Amount: $0.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Timeline
Solicitation Year: N/A
Award Year: 2001
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
160 COMMONWEALTH AVE, STE 801 BOSTON, MA 02116
BOSTON, MA 02116
United States
DUNS: N/A
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 KEVIN MCINTYRE
 (617) 266-6681
 SIMPRES@AOL.COM
Business Contact
Phone: (617) 266-6681
Email: SIMPRES@AOL.COM
Research Institution
 HARVARD MEDICAL SCHOOL (VAMC)
 
UNIVERSITY OF MISSOURI-ROLLA
WEST ROXBURY, MA 01834
United States

 Nonprofit College or University
Abstract

For over 4 million Americans with Alzheimer's disease and related disorders (ADRD), there is no effective therapy to interrupt or slow disease progression. Negative behaviors, apathy and sadness, communicate confusion, pain and discomfort impose tremendous burden on family and other caregivers. Our innovative "Simulated Presence" (SimPres(TM)) intervention uses selected memory clusters and a novel technology to create a personalized environment that enhances quality of life for ADRD persons, and provide family and other care providers a viable management alternative. SimPres is presented to ADRD persons via an inexpensive, personalized, interactive audiotape -- rich in selected memories and positive emotions, that contains one side of a "live" telephone conversation with a family member or surrogate. Phase I studies the feasibility of training family "callers" cost-effectively, with subjects drawn from different study sites. In Phase II, a Latin-squares cross-over design with assess the effectiveness of three treatments (family-made, staff-made and placebo tapes) to improve well-being, applied over three time periods, in three research sites (nursing facilities, assisted living, adult day health). Well-being is assessed through direct observation, video rating, and staff report of engagement, mood, agitation, compliance with personal care. Perceived benefits to family (enhanced means of communication, improved understanding of ADRD person) will also be assessed.
PROPOSED COMMERCIAL APPLICATION:
We believe SimPres will provide an individualized approach to improve well-being in persons with dementia. Specifically, we expect that, SimPres will (1) decrease problem behaviors; (2) lower the economic costs of care by delaying institutionalization, decreasing medication use, and decreasing nursing staff turnover; and (3) decrease burdens felt by family and staff.

* Information listed above is at the time of submission. *

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