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Ultrasensitive Molecular Identifier

Award Information
Agency: Department of Health and Human Services
Branch: N/A
Contract: 1 R43 ES06853-1,
Agency Tracking Number: 25052
Amount: $74,992.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: N/A
Solicitation Number: N/A
Solicitation Year: N/A
Award Year: 1994
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
30A Cherry Hill Drive
Danvers, MA 01923
United States
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Kenneth Purser
 (508) 750-8455
Business Contact
Phone: () -
Research Institution

Detection and tracking of toxic chemicals often employs the use of radio-isotopes as a moleculartag. The sensitivity of radioisotope tracking has been drastically improved over the past decade throughthe use of accelerator mass spectroscopy (AMS). Present enhancement factors for trace isotopes areas large as l.OE+09 in the case of 129-I. While extremely useful for a wide range of applications, theAMS measurements have limitations in their lack of molecular structural information. A method isproposed to design a compact commercial detection system which will provide the sensitivity of AMSand will also yield such molecular structural data. A liquid or gas chromatograph stage will be used forinput into a pyrolyzing ion source system. The new instrument will operate in a standard laboratoryenvironment, produce no radiation, and will fit in an area of <5x3m. Phase I will concentrate onmachine design for l4-C detection. The Phase II will provide a complete assembly and testing of thecompact detection system for a wide molecular range. This R&D will provide an attractive instrumentfor a commercial system, viable in a variety of biomedical fields.

* Information listed above is at the time of submission. *

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