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Deployable Intracranial Sensor Array

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-06-C-0400
Agency Tracking Number: A064-028-0170
Amount: $99,972.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: A06-T028
Solicitation Number: N/A
Solicitation Year: 2006
Award Year: 2006
Award Start Date (Proposal Award Date): 2006-09-11
Award End Date (Contract End Date): 2007-08-10
Small Business Information
303 Bear Hill Road
Waltham, MA 02451
United States
DUNS: 004627316
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Anna Galea
 (781) 890-1339
Business Contact
 William Thompson
Title: Contracts Official
Phone: (781) 890-1338
Research Institution
 Norman Dean
300 Longwood Ave
Boston, MA 02115
United States

 (617) 355-6005
 Domestic Nonprofit Research Organization

Cortical Spreading Depression (CSD) as a secondary phenomenon to traumatic head injury can herald further brain tissue damage well after the initial injury. The only way to reliably record CSD is through direct electrode contact with the brain. With modern equipment this requires that the skull and dura be removed, which is only feasible in a small number of patients. Infoscitex and our partners at Children’s Hospital Boston propose a novel subdural electrode array capable of being inserted through a standard hole used for intra-cranial pressure (ICP) monitoring. One of our arrays alone can cover 6 cm2 of cortical tissue, and has electrodes spaced up to 1 cm apart. The design of our array is ideal for recording the low-frequency waves of CSD. Our array will be beneficial in cases both of traumatic head injury and also brain injuries from stroke. The potential benefits to monitoring for CSD in all patients who require ICP monitoring is vast, due to the number of potential patients and the high incidence of secondary injury. The team assembled for this program involves experts in the field of subdural electrode placement and signal recording, as well as considerable experience in developing minimally invasive medical devices.

* Information listed above is at the time of submission. *

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