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Allergens and Induced Asthma: Eradicating Indoor Allergens and Dust Mites

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43ES019790-01
Agency Tracking Number: R43ES019790
Amount: $129,819.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NIEHS
Solicitation Number: PA10-050
Solicitation Year: 2011
Award Year: 2011
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
United States
DUNS: 808418276
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (803) 520-3830
Business Contact
Phone: (803) 520-3830
Research Institution

DESCRIPTION (provided by applicant): Allergens and Induced Asthma: Eradicating Indoor Allergens and Dust Mites The mission of CarboNix LLC is the clinically effective abatement of common indoor allergens that cause allergic reactions and frequently induceasthma, especially in children. The focus of this project is on the dust mite. Carbonix LLC proposes a Phase I research program, leading to a commercialization of a new service business for killing dust mites in the home and preventing re-infestation. Three specific aims are proposed to demonstrate feasibility. Specific Aim 1 will demonstrate that treating carpets with our proprietary technology will physically kill dust mites. Specific Aim 2 will demonstrate that an acaricide can be incorporated in the process, penetrating carpeting and preventing mite re-infestation. Specific Aim 3 will demonstrate the Carbonix process on mattresses, the other main repository of mites in the home. The dust mite is second only to pollen in causing allergies. Reactions rangefrom itchy noses and eyes to severe and sometimes fatal asthma attacks. This is especially critical in children under age 13. This project could benefit any allergy sufferer, but is specifically aimed at minority and low-income children who are six timesmore likely to die from dust mite allergen-induced asthma. The American Lung Association estimates that 32.5 million Americans (approx. 11.2%) have been diagnosed with asthma, and 6.2 million of these are children between 5 and 17. It has been shown that most children with exacerbation of asthma have been exposed to high levels of indoor allergens, and that continuous exposure can result in readmission. The National Center for Health Statistics showed that the prevalence of asthma in minority (specificallyAfrican American and Puerto Rican) children is 40% higher than in white children. We will create a new service business, similar in operation and cost to carpet cleaning services, for families and their allergists; namely, complete removal and deactivationof dust mites from the home environment. Clinicians often employ a multiple-intervention strategy for allergy and asthma management. The new business will give practicing clinicians a new interventional tool, namely the safe and inexpensive cleaning of allergen- laden household items. PUBLIC HEALTH RELEVANCE: Eradication of Dust Mites and Removal of Allergens in Carpeting Asthma is a killer of children; especially those from disadvantaged homes. Many asthma attacks, especially in children, are triggered by the allergenic proteins found in dust mite feces. The proposed research focuses on a novel, clean, safe and effective approach to eradicating dust mites in carpeting and other large fabric surfaces.

* Information listed above is at the time of submission. *

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