You are here

Pathogen Identification of Wounds Via Bead-Based Multiplexing

Award Information
Agency: Department of Defense
Branch: Defense Health Agency
Contract: W81XWH-12-C-0080
Agency Tracking Number: O2-1345
Amount: $999,874.00
Phase: Phase II
Program: SBIR
Solicitation Topic Code: OSD11-H16
Solicitation Number: 2011.2
Solicitation Year: 2011
Award Year: 2013
Award Start Date (Proposal Award Date): 2013-06-11
Award End Date (Contract End Date): 2015-11-15
Small Business Information
P.O. Box 2607
Winnetka, CA -
United States
DUNS: 082191198
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Karyn Apfeldorf
 Principa Investigator
 (818) 885-2200
Business Contact
 David Campion
Title: Vice President
Phone: (818) 885-2200
Research Institution

Arete Associates and Luminex Corporation propose a Phase II SBIR effort to develop a portable, Point-of-Care system that enables rapid identification of known and de novo pathogens in wounds. The proposed system, which leverages Luminex"s award-winning bead-based multiplexing technology and Arete"s advanced bioinformatics algorithms, provides pathogen identification and antibiotic resistance information for targeted treatment. The proposed work builds on key results from Phase I, including: (a) proof-of-concept demonstration of an algorithmic technique to detect antibiotic resistance signatures that can be exploited for assay design, (b) feasibility demonstration of streamlined multiplex assays for wound pathogen identification with the ability to optionally add protein assays, and (c) establishment of a strong foundation for rapid multiplex cytokine and pathogen detection through an efficient, simple workflow with low levels of detection for both purified and complex (in-context) sample matrixes.

* Information listed above is at the time of submission. *

US Flag An Official Website of the United States Government