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DIPAIN based assay for the T-2 Toxin

Award Information
Agency: Department of Defense
Branch: Army
Contract: W911SR-10-C-0061
Agency Tracking Number: A10A-021-0083
Amount: $100,000.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: A10A-T021
Solicitation Number: 2010.A
Solicitation Year: 2010
Award Year: 2010
Award Start Date (Proposal Award Date): 2010-09-20
Award End Date (Contract End Date): 2011-03-20
Small Business Information
225 Long Avenue Building 15
Hillside, NJ 07205
United States
DUNS: 036081185
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Nicolai Panikov
 Principal Scientist
 (973) 923-3028
Business Contact
 Ou Li
Title: Vice President
Phone: (973) 923-3028
Research Institution
 Marshall University
 Chris Schlenker
401 11th Street, Suite 1400
Huntington, WV 25701
United States

 (304) 696-4307
 Nonprofit College or University

This proposed project is to develop a rapid assay for T-2 Toxin. Under this project we will develop DIPAIN-derivative based test-strips that indicate the presence of trace quantities of trichothecene mycotoxins in aqueous solutions. The T-2 toxin will be used as a test case for this effort. We will use of 2-(diphenylacetyl)-l,3-indanedione-l-hydrazone (DIPAIN II) and its derivatives as reagents on solid supports, using the property that DIPAIN derivatives undergo significant fluorescence enhancement in the visible range under UV excitation when in contact with trichothecene mycotoxins and that the presence of the toxin is indicated by the enhanced fluorescence of the DIPAIN derivative.

* Information listed above is at the time of submission. *

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