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Bacteriocin Based Antimicrobials for Textile Applications

Award Information
Agency: Department of Defense
Branch: Army
Contract: W911NF-14-P-0017
Agency Tracking Number: A14A-012-0076
Amount: $150,000.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: A14A-T012
Solicitation Number: 2014.A
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): 2014-08-01
Award End Date (Contract End Date): 2015-02-07
Small Business Information
VA Suite 400
Roanoke, VA 24016-4962
United States
DUNS: 627132913
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Siqi Li
 Principal Investigator
 (434) 483-4230
Business Contact
 Maggie Hudson
Title: Senior Contracts Administrator
Phone: (434) 483-4254
Research Institution
 University of California, San Diego
 Shelby M JD
9500 Gilman Dr. #0934 Torrey Pines Center N, Level 3
La Jolla, CA 92093-0934
United States

 (858) 534-3331
 Nonprofit College or University

Antimicrobial treatments have been incorporated in a number of textile products used by the U.S. Army to control odor and reduce skin irritation, thus improving the quality of life for the warfighters. Current textile treatment using chemically-derived antimicrobials such as metals (silver- and copper-based compounds), polyphenols, halamines and quaternary ammonium compounds can effectively kill odor-generating Corynebacteria and skin-itching Staphylococcus aureus, however they also have significant drawbacks. To address this issue, Luna is developing a narrow-spectrum antimicrobial textile coating product based on bacteriocin molecules with proven potency and specificity and Luna"s existing polymer coating technique. During the three-phase program, Luna plans to prove its concept through testing bacteriocin antimicrobial potency and specificity in a solution-based system in Phase I. The lead bacteriocin, hemolytic and cytoxicity activities, skin permeability and production scalability, will be established. During Phase II, the bacteriocin production and coating on fabrics will be optimized and prototype fabrics will be developed and evaluated, followed by integrating with current antimicrobial textiles and evaluating for commercialization in Phase III. The project will result in antimicrobial textiles with controlled skin irritation and malodor, thereby improving the life quality of warfighters.

* Information listed above is at the time of submission. *

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