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Novel Polymer Matrix for Dental Applications

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43DE024013-01
Agency Tracking Number: R43DE024013
Amount: $182,536.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NIDCR
Solicitation Number: PA13-088
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
12345 W 52ND AVE
WHEAT RIDGE, CO 80033-1916
United States
DUNS: 181947730
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (303) 940-2338
Business Contact
Phone: (303) 940-2300
Research Institution

DESCRIPTION (provided by applicant): Dental caries are the most common childhood disease in the United States. Dental sealants are materials that are applied to the pits and fissures of healthy teeth to prevent dental caries or other forms of decay. This method prevents bacteria ingress and acid dissolution and targets the portions of the tooth surface where ~90% of the decay develops. Peer-reviewed research incontrovertibly substantiates that sealants are safe and effective in preventing caries on both primary and permanent teeth (gt 90% reduction in caries on the sealed surface). The application of sealants is minimally invasive, painless and is typically well-accepted by patients, and sealants are a valuable tool to reduce overall dental care costs. Two major classes of materials have been used as sealants: glass ionomers and resins based sealants. Glass ionomers release fluoride that provides some antimicrobial and re-mineralization activity; however they have a higher water uptake, poorer retention and hi

* Information listed above is at the time of submission. *

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