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Nanobind FFPE DNA/RNA Extraction

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R43ES024180-01
Agency Tracking Number: R43ES024180
Amount: $224,338.00
Phase: Phase I
Program: SBIR
Solicitation Topic Code: NIEHS
Solicitation Number: ES13-009
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
810 Wyman Park Drive
BALTIMORE, MD 21211-2840
United States
DUNS: 830377581
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 KELVIN LIU
 (626) 202-4825
 kliu@circulomics.com
Business Contact
 KELVIN LIU
Phone: (626) 202-4825
Email: kliu@circulomics.com
Research Institution
 Stub
Abstract

DESCRIPTION (provided by applicant): Nanobind FFPE DNA/RNA Extraction Despite the growing need for and the demonstrated potential advantages of molecular biomarkers, it has proven difficult to routinely employ them in the diagnosis and management of patients. One reason for this failure has been the logistical challenges of obtaining, rapidly processing, storin, and transporting quick-frozen tissue samples in clinical settings. Standard hospital tissue processing involves fixation in formaldehyde, followedby embedding in paraffin blocks to generate Formalin Fixed Paraffin Embedded (FFPE) tissue samples. If these FFPE samples can be harnessed for routine molecular analysis, the potential for revolutionizing current medical practice exists. FFPE blocks obtained in hospital pathology departments could then be routinely assayed using the newer molecular methods. Moreover, since FFPE samples are usually stored for many years by hospital pathology departments, retrospective molecular evaluations could also be

* Information listed above is at the time of submission. *

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