You are here

Development of small near-infrared laser system capable of improving immune respo

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41AI114012-01
Agency Tracking Number: R41AI114012
Amount: $146,905.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NIAID
Solicitation Number: PA13-235
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
100 CORPORATE PL, STE 401
PEABODY, MA 01960-3809
United States
DUNS: 135220635
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 JOHN CALLAHAN
 (978) 326-7701
 jcallahan@seminex.com
Business Contact
 DAVID BEAN
Phone: (978) 326-7701
Email: dbean@seminex.com
Research Institution
 MASSACHUSETTS GENERAL HOSPITAL
 
Partners Research Management 101 Huntington Ave, Suite 300
BOSTON, MA 02199-7603
United States

 () -
 Domestic nonprofit research organization
Abstract

DESCRIPTION (provided by applicant): The broad and long-term objective of this project is to amplify the effectiveness of vaccines without the use of chemical or biological adjuvants. We will address this objective by demonstrating the feasibility for small laser- based devices to enhance responses to intradermal vaccination. A number of investigators have shown that a promising new way to make vaccines work better is to treat the skin with a brief exposure to a non-harmful laser light and then introduce the vaccine at that skin site. This approach can result in better vaccine responses without the need for chemical adjuvants. Until now, these responses have been generated using large and relatively expensive bench top devices. Recently, low-power, near-infrared (NIR) laser light has also been shown to significantly enhancing vaccine responses. This would make it possible to use small, low-cost NIR laser systems to enhance vaccines that would be practical in the clinical setting. There are currently

* Information listed above is at the time of submission. *

US Flag An Official Website of the United States Government