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Surface-covering gels for broad-spectrum antimicrobial protection following open

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41AR065917-01
Agency Tracking Number: R41AR065917
Amount: $149,967.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NIAMS
Solicitation Number: PA13-089
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
CHANDLER, AZ 85226-3865
United States
DUNS: 78413884
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 (480) 965-0929
Business Contact
Phone: (520) 280-3237
Research Institution
*(FY72 USE 0488301)
TEMPE, AZ 85281-
United States

 () -
 Nonprofit college or university

DESCRIPTION (provided by applicant): About 3-4% of all fractures are estimated to be open fractures, where the fracture is exposed through defects in the skin and soft tissues. This equates to about 250,000 open fractures in the United States annually. Open fractures present a high risk of infection. Infection results in considerable financial burden to both the patient an healthcare system, requires repeat operations (often more than one), and can cause delayed fracture healing or nonunion. There is no suitable option available for local antimicrobial deliver to many open fractures. A biocompatible local delivery vehicle with a fast degradation time could provide effective coverage to a much wider range of open fractures than possible with available materials. Such a technology would provide a real benefit to patients and healthcare providers alike. A promising approach for preventing infections following open fractures is to use a resorbable controlled release carrier, SB Gel, for the sustained relea

* Information listed above is at the time of submission. *

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