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Novel Therapeutic Opportunity in Stroke

Award Information
Agency: Department of Health and Human Services
Branch: National Institutes of Health
Contract: 1R41NS087684-01
Agency Tracking Number: R41NS087684
Amount: $225,000.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: NINDS
Solicitation Number: PA13-235
Timeline
Solicitation Year: 2014
Award Year: 2014
Award Start Date (Proposal Award Date): N/A
Award End Date (Contract End Date): N/A
Small Business Information
10225 Barnes Canyon Road suite A104
SAN DIEGO, CA 92121-2734
United States
DUNS: 963248807
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 VICTOR UTESHEV-GAARD
 (858) 657-0918
 Victor.Uteshev@unthsc.edu
Business Contact
 GRAHAM BEATON
Phone: (858) 657-0918
Email: gbepigen@gmail.com
Research Institution
 UNIVERSITY OF NORTH TEXAS HLTH SCI CTR
 
UNIVERSITY OF NORTH TEXAS HEALTH SCIENCES CENTER 3500 CAMP BOWIE BLVD
FORT WORTH, TX 76107-2699
United States

 () -
 Nonprofit College or University
Abstract

DESCRIPTION (provided by applicant): Stroke is a leading cause of death and disability in the USA, yet widely effective treatments remain elusive and, except for a lengthy program of rehabilitation, no effective treatment for cerebral ischemic stroke is available. Therefore, there s a critical need in new therapeutic approaches which can maximally preserve ischemic penumbra and facilitate functional recovery. In the last two decades substantial efforts have been invested in developing anti-stroke medicine,but these efforts have not resulted in clinically-efficacious therapies for stroke. These failures highlight the need for development of new therapeutic ideas and approaches for prevention of neuronal injury secondary to ischemia and stroke. Among possible strategies, effective post-stroke treatments with broad therapeutic windows are likely to be the most valuable because of the unexpected nature of stroke. The existing literature and preliminary data presented indicate that activation of 7 nicotinic

* Information listed above is at the time of submission. *

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