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Development of novel wound dressing technology combining advanced hydrogel and perfusion enhancement technologies.

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-15-C-0040
Agency Tracking Number: A14A-016-0166
Amount: $149,373.00
Phase: Phase I
Program: STTR
Solicitation Topic Code: A14A-T016
Solicitation Number: 2014.1
Solicitation Year: 2014
Award Year: 2015
Award Start Date (Proposal Award Date): 2015-07-31
Award End Date (Contract End Date): 2015-08-15
Small Business Information
46 Russell Street Suite 1
Brookline, MA 02446
United States
DUNS: 830000019
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Shai Schubert
 chief scientific officer
 (617) 331-7524
Business Contact
 Shai Schubert
Title: Dr
Phone: (617) 331-7524
Research Institution
 Brigham and Womens Hospital - MIT
 Rachel Abrams
101 Huntington Avenue 4th Floor
Boston, MA 02199
United States

 (617) 954-9391
 Nonprofit College or University

Complex wounds including traumatic, chemical, chronic or surgical wounds present a significant challenge to care givers. Wound healing, being a complex and multifaceted process, differs significantly based on the type of wound and the underlining health of the patient. It is well established that factors like impaired perfusion, infection, existence of metabolic disorders such as diabetes, bad nutrition and smoking can significantly impair wound healing. While the cause for delayed healing may differ, some basic factors remain critical for all wounds. These include sufficient perfusion, pH regulation, electrolyte balance, detoxification, and nutrition. Perfuzia medical developed ActiveFlow, an active perfusion/oxygenation stimulation technology designed for wound healing. In the present project we will develop a novel combination topical wound healing device that will combine advanced topical wound treatment for optimization of wound bed conditions, management of wound exudates and delivery of therapeutic agents to the wound bed with the ActiveFlow perfusion technology for increased perfusion and oxygenation. Combination of increased local perfusion and oxygenation, together with advanced topical treatment is expected to result in a synergistic therapeutic effect and improvement in wound healing time and quality.

* Information listed above is at the time of submission. *

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