Development of novel wound dressing technology combining advanced hydrogel and perfusion enhancement technologies.

Complex wounds including traumatic, chemical, chronic or surgical wounds present a significant challenge to care givers. Wound healing, being a complex and multifaceted process, differs significantly based on the type of wound and the underlining health of the patient. It is well established that factors like impaired perfusion, infection, existence of metabolic disorders such as diabetes, bad nutrition and smoking can significantly impair wound healing. While the cause for delayed healing may differ, some basic factors remain critical for all wounds. These include sufficient perfusion, pH regulation, electrolyte balance, detoxification, and nutrition. Perfuzia medical developed ActiveFlow, an active perfusion/oxygenation stimulation technology designed for wound healing. In the present project we will develop a novel combination topical wound healing device that will combine advanced topical wound treatment for optimization of wound bed conditions, management of wound exudates and delivery of therapeutic agents to the wound bed with the ActiveFlow perfusion technology for increased perfusion and oxygenation. Combination of increased local perfusion and oxygenation, together with advanced topical treatment is expected to result in a synergistic therapeutic effect and improvement in wound healing time and quality.