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Soft and Elastomeric Intramuscular Electrode with Therapeutic Delivery Capability

Award Information
Agency: Department of Defense
Branch: Army
Contract: W81XWH-13-C-0157
Agency Tracking Number: A2-5778
Amount: $999,983.00
Phase: Phase II
Program: STTR
Solicitation Topic Code: A13A-T019
Solicitation Number: 2013.0
Solicitation Year: 2013
Award Year: 2015
Award Start Date (Proposal Award Date): 2015-01-15
Award End Date (Contract End Date): 2017-01-14
Small Business Information
12345 W. 52nd Ave.
Wheat Ridge, CO 80033-1916
United States
DUNS: 181947730
HUBZone Owned: No
Woman Owned: No
Socially and Economically Disadvantaged: No
Principal Investigator
 Silvia Luebben
 Principal Chemist
 (303) 940-2317
Business Contact
 John Wright
Title: DR
Phone: (303) 940-2300
Research Institution
 University of Pittsburgh
 Dr. Tracy Cui
5057 Bioscience Tower 3 3501 Fifth Avenue
Pittsburgh, PA 15260-3543
United States

 (412) 383-6672
 Nonprofit College or University

Approximately 5-6% of military injuries involve some form of major peripheral nerve injury that has little chance of spontaneous healing. Currently these injuries lead to major impairment of voluntary muscle function in the limbs and extremities, making tasks of walking, reaching, grasping, etc. very difficult or impossible for many patients. Focusing therapeutic treatments to segmental nerve injuries alone is insufficient as distal muscles may undergo denervation and atrophy following nerve trauma. Therefore, new methods to treat and stimulate the distal neuromuscular junctions (NMJs) during the proximal axonal regeneration process must be developed to maintain muscle viability for subsequent innervation and functionality. TDA Research, Inc. (TDA) and our partners at the Univ. of Pittsburgh (UP) are developing soft, flexible, neuromuscular electro-stimulation (ES) prosthetics with elastic composite electrodes and controlled release of neurotransmitters and growth factors to maintain healthy muscle function and promote reinnervation at the NMJs.

* Information listed above is at the time of submission. *

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