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Quick-Med Technologies, Inc.

Address

902 NW 4th St
Gainesville, FL, 32601-4285
USA

UEI: CAGMXNKG7XJ1

Number of Employees: 5

HUBZone Owned: No

Woman Owned: No

Socially and Economically Disadvantaged: No

SBIR/STTR Involvement

Year of first award: 2005

Phase I Awards

Phase II Awards

28.57%

Conversion Rate

$965,949

Phase I Dollars

$1,130,000

Phase II Dollars

$2,095,949

Total Awarded

Awards

Up to 10 of the most recent awards are being displayed. To view all of this company's awards, visit the Award Data search page.

Stay-Fresh long-term disinfectant coatings for high-touched surfaces based on hydrogen peroxide as the active agent.

Amount: $400,000 Topic: 4A

The COVID-19 pandemic has evidenced the pressing and substantial need for sustainable and more effective solutions to prevent the transmission and spreading of pathogens of public health concern, including the SARS-CoV-2. Imminent challenges for the US Nation include emerging pathogens resulting from disease outbreaks or manufactured and released by terrorists. In this regard, high-touch surfaces in high traffic areas represent a particular public health challenge. Cost effective disinfectant coatings with long-term efficacy are sorely needed in the fight of pandemics and other biological threats. Stay-Fresh is a surface coating developed by Quick-Med Technologies that offers a safe, effective, and durable antimicrobial/antiviral protection. The innovation of Stay-Fresh technology is in the reversible binding of hydrogen peroxide (HP) within a complex of zinc oxide, which sequesters HP into a non-volatile form that can bind tightly to fibers as well as non-porous surfaces. In the presence of moisture, HP is released in a controlled manner, creating a highly localized yet potent �kill zone� for viruses and bacteria. Through controlled release, Stay-Fresh provides unparalleled antimicrobial effect, outperforming other formulations in terms of cost, efficacy, ease-of-use and durability. As opposed to alternative antimicrobials, the active agent in Stay-Fresh, HP, does not entail any hazard to human health or environmental impact. HP is naturally produced by both animal and plant cells, and concentrations present in the proposed solution are within the safe CDC guidelines. Moreover, the ease of use of the Stay-Fresh solution allows for the treatment to be readily applied without complicated equipment and stable long-term storage of the product until needed. During Phase I QMT has tested Stay-Fresh on typical hard surfaces used in high traffic areas and verified the short- and long-term efficacy of Stay-Fresh according to EPA recently released guidelines for Evaluating the Efficacy of Antimicrobial Surface Coatings. Target customers of Stay-Fresh technology include facility managers and cleaning service providers of public transportation infrastructure, municipalities, healthcare providers, and other high-touch/high-volume areas such as schools, commercial buildings, industry settings, office buildings and more. Antimicrobial coatings hold a market share of 16% of the global smart coatings market (USD 0.49 billion in the year 2020) and is forecasted to have an annual growth rate of 19.1% reaching USD 1.98 billion in 2028. North America represents a substantial 25% share of this market.

SBIR

Phase II

2022

EPA

SBIR Phase I: Regenerable Antimicrobial Paints Based on Hydrogen Peroxide

Amount: $255,999 Topic: BM

The broader impact of this Small Business Innovation Research (SBIR) Phase I project will be to reduce and prevent surface-based transmission of pathogens and thereby help public and institutional spaces become cleaner and safer, especially for at-risk populations. Hospital-acquired infections can be prevented by killing bacteria, molds, and fungi; and inactivating viruses on surfaces before they are able to pass to another person. The project will develop antimicrobial paints based on hydrogen peroxide (HP), which does not have toxic degradation products since it turns into water and oxygen. HP has a long history of safe use, without allowing generation of resistant strains of infectious organisms. The paints can improve hygiene, and allow more efficient cleaning with peroxide-based agents, from which the paints can regenerate their antimicrobial efficacy, providing durable protection without highly toxic chemical applications. Competing antimicrobial paints are expensive, have not demonstrated long-term antimicrobial activity, or have used chemistries that carry the risk of developing microbial resistance. The proposed peroxide based antimicrobial paint will be more affordable, and very safe to implement, allowing regeneration of efficacy during cleaning. This will enable more widespread use in public health and institutional settings to help protect against transmissible infections. The proposed project addresses the technical challenge of developing an antimicrobial paint that can be regenerated, based on the use of HP in the formulation to achieve broad-spectrum antimicrobial and virucidal activity with long-term efficacy. This project leverages new technology to produce paint coatings that can sequester HP into a coated surface in a dry non-volatile form. This enables the slow release of HP over time that can be regenerated by exposure to commercially available solutions containing HP. HP degrades into innocuous products. Bacteria and viruses are not able to develop resistance to its disinfecting mechanism. Hence, the resulting product and its regeneration process will be long-lasting, cost-effective and environmentally safe. Technical challenges to be addressed in this project include ensuring formulation stability, antimicrobial and virucidal potency and recharging functionality of the paint, and the effects of HP on paint integrity. The team will closely collaborate with specialty coatings experts to develop and test viable paint formulations. Anticipated technical results include a prototype version of the technology, and documentation of the research outcomes and further regeneration requirements. This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

SBIR

Phase I

2021

NSF

Stay-Fresh long-term disinfectant coatings for high-touched surfaces based on hydrogen peroxide as the active agent

Amount: $99,968 Topic: 20-OSAPE-4A

The current COVID-19 pandemic has evidenced the pressing and substantial need for sustainable and more effective solutions to prevent the transmission and spreading of pathogens of public health concern, including the SARS-CoV-2 virus that causes COVID-19. High-touch surfaces in high traffic areas represent a particular public health challenge. Cost effective disinfectant coatings with long-term efficacy are sorely needed. Stay-Fresh coatings developed by Quick-Med Technologies offers communities safe, effective, and durable antimicrobial/antiviral protection. The innovation of Stay-Fresh technology is in the reversible binding of hydrogen peroxide (HP) within a complex of zinc oxide, which sequesters HP into a non-volatile form that can bind tightly to fibers as well as nonporous surfaces. In the presence of moisture, HP is released in a controlled manner, creating a highly localized yet potent “kill zone”. Through controlled release, Stay-Fresh provides unparalleled antimicrobial effect, outperforming other formulations in terms of cost, efficacy, ease-of-use and durability. As opposed to other active agents, HP does not entail hazard to human health or environmental impact. Products containing other antimicrobials are known to be related to asthma, dermatitis, and allergies. In addition, they can be washed down the drain or improperly disposed of, representing a potential threat to both the environment and wildlife. In contrast, HP is naturally produced by both animal and plant cells, and concentrations present in the proposed solution are within the safe CDC guidelines. Target customers of Stay-Fresh technology include public transportation companies, municipalities, health and environmental organizations, and other high-touch/high-volume areas such as hospitals, schools and playgrounds, retail merchants, industry settings, office buildings and more. The ease of use of the Stay-Fresh solution is another advantage of the innovation. The treatment can be readily applied without complicated equipment to achieve instantaneous disinfection and durable antimicrobial/antiviral efficacy on treated products, and allows stable long-term storage of the product until needed. Long-lasting antimicrobials held a market share of 16% of the global “smart” coatings market in 2018 and are expected to experience a rapid annual growth rate of over 19% in the 2018-2026 period. The global market of antimicrobial coatings is forecasted to reach $18.8 billion by 2027, at a CAGR of 12.8%. The U.S. is expected to represent a substantial share of the global market. Stay-Fresh is an innovative solution to a global problem that holds excellent long-term disinfectant properties and favorable market potential

SBIR

Phase I

2021

EPA

Open Call for Innovative Defense-Related Dual-Purpose Technologies/Solutions with a Clear Air Force Stakeholder Need

Amount: $49,982 Topic: AF193-CSO1

Quick-Med Technologies, Inc. (Gainesville, FL) is an innovative life sciences company specializing in the development of next-generation antimicrobial technologies for the healthcare, consumer, and Government markets. Quick-Med (QMT) has developed the world's most advanced antimicrobial technologies that combat microbial growth in a variety of broad-based products. Our technology is always designed to be safe for the environment and public health. By utilizing biomimetic chemistries, broad and long-lasting antimicrobial efficacy can be provided at affordable cost, without concern about bacterial resistance, or environmental toxicity.

SBIR

Phase I

2020

DOD

USAF

Antimicrobial Absorbent Pad for Reducing Bacterial Contamination of Packaged Poultry

Amount: $150,000 Topic: FDA

DESCRIPTION provided by applicant The CDC has reported that each year over million Americans are affected by food contamination which results in more than hospitalizations and more than deaths A significant percentage of these incidents result from contaminated meat and poultry products which are routinely tray packaged for retail sale These tray packs almost always contain one or two absorbent pads which absorb and retain the andquot purgeandquot or the juices blood and other fluids that seep from the meats This purge is unsightly for the consumer leaks is messy and most importantly it is often contaminated with bacteria Quick Med Technologies Inc QMT Gainesville FL has developed a novel and patent pending antimicrobial superabsorbent polymer SAP based on our proprietary sequestered hydrogen peroxide HP technology known as Stay Fresh r QMT will prepare prototype absorbent pads containing the Stay Fresh superabsorbent antimicrobial at various concentrations The prototype pads will be extensively characterized for antimicrobial performance and a nationally recognized food safety laboratory will assist in evaluation of actual shelf life and microbial content of meats packaged using the antimicrobial absorbent pads Hydrogen peroxide is favored in many applications because its breakdown products water and oxygen are innocuous and it tends to have broad spectrum antimicrobial activity This represents a andquot leap aheadandquot technology that will not only improve food safety and public health but the small incremental costs andlt of the total packaging costs will be more than offset by the extended shelf life of the product The favorable economics of this innovation will help drive rapid commercialization PUBLIC HEALTH RELEVANCE Food poisoning caused by bacteria in meat and poultry sickens or even kills many people each year By incorporating Hydrogen Peroxide in a dry highly absorbent form into the pads used to soak up the juice in foam supermarket meat trays we can eliminate bacteria and ensure safe and healthy food for everyone Hydrogen peroxide is a safe and environmentally friendly alternative to the use of toxic chemicals

SBIR

Phase I

2015

HHS

FDA

SBIR Phase I: Regenerable Antimicrobial Coatings Containing Zinc Oxide Binders for Hydrogen Peroxide Cleaning Solutions

Amount: $150,000 Topic: BC

This Small Business Innovation Research (SBIR) Phase I project proposes to develop novel polymer coatings that bind hydrogen peroxide (HP), even after the surface has dried, thus maintaining sanitized surfaces and preventing microbial growth and the spread of disease. This allows the surface to maintain long-lasting antimicrobial effects between cleanings. It is expected that these coated surfaces will kill 99.999% of microbes that contact the surface. HP is currently receiving renewed attention as a safe, environmentally-friendly, and cost-effective antimicrobial, as evidenced by the recent introduction of several commercially-available cleaning products based on HP. Healthcare facilities are known to be breeding grounds for a variety of infectious diseases. The pathogens that cause these diseases can reside in many places in the hospital environment ? not just in devices and equipment used in medical procedures, but also from common surfaces such as bed rails, bathroom fixtures, hand rails, and computer keyboards. Microbes living on these contaminated surfaces, which are touched by multiple people, lead to increased spread of healthcare associated infections (HAIs). It is estimated that 1 in 20 hospital patients will be infected with an HAI as a direct result of the care they receive in the hospital. The broader impact/commercial potential of this project go beyond the medical and hospital applications for which the coatings will be developed and the potential for use in other areas are enormous, with broad utility in the consumer, industrial, and institutional markets. Multiple people touching everyday objects spread infection and disease. One dirty hand can infect numerous surfaces. Rubbing one?s eye or eating a sandwich can become a vector for infection. Even surfaces that are cleaned and sanitized frequently can quickly become recontaminated after the applied disinfectant has evaporated. Examples of places where such coatings would have great impact on public health include bathroom fixtures in public restrooms; kitchen equipment and tables in restaurants, schools and other institutions; home appliances; and seats, armrests, railings, and tray tables for airlines, cruise ships, and other public transportation. Such coatings could be easily implemented into existing manufacturing processes, retrofitted to existing equipment, or even sold as paints for DIY use. The commercial potential for these coatings is huge, especially in consideration of the potential savings to the healthcare industry. A 20% percent reduction in HAI?s translates into an annual savings of $7.2 million, demonstrating that money spent on preventative steps translates into meaningful savings.

SBIR

Phase I

2013

NSF

Development of Technologies that Control Scar Contracture after Burn Injuries

Amount: $150,000 Topic: DHP12-016

Current therapies to prevent scar formation and contracture of burns are minimally effective. QuickMed Technologies (QMT) proposes to develop an advanced therapy to enhance healing and prevent contraction of burn scars by combining the advanced prototype BURN-PLUS dressing with Endoform dermal template. BURN-PLUS is an occlusive island dressing with an adhesive apron bonded onto a super absorbent, microbicidal, pad that provides sustained release of two pre-loaded, FDA-cleared drugs: doxycycline and Kepivance. Doxycycline is a broad spectrum antibiotic that also reduces inflammation through inhibition of tumor necrosis factor alpha (TNFa) converting enzyme (TACE) and inhibits contraction of collagen lattices by myofibroblasts through its inhibition of matrix metalloproteinases (MMPs). Kepivance is keratinocyte growth factor (KGF), which accelerates healing of skin wounds by directly stimulating proliferation and migration of epithelial cells. Endoform is a novel acellular matrix that has intact extracellular matrix (ECM) components (collagen IV, laminin, fibronectin) and growth factors (FGF2, VEGF) that increases vascularization and decreases irregular scar matrix in pig skin wounds. In this Phase I project, QMT will optimize design components of BURN-PLUS dressing and test its effectiveness alone and combined with Endoform matrix on enhancing healing and reducing scar formation and contracture of burn wounds in pigs.

SBIR

Phase I

2013

DOD

DHA

Chemical Casualty Care: Wound Dressings Designed to Speed Wound Closure Following Debridement of Cutaneous Vesicant Injuries

Amount: $730,000 Topic: A05-131

Quick-Med Technologies (QMT) has shown proof of concept for an advanced wound care dressing to speed healing of partial thickness skin wounds in vesicant injured patients, specifically for application after skin debridement. This wound dressing is antimicrobial and superabsorbent to provide moist wound healing while protecting from bacterial infection, including resistant species. The wound dressing speeds healing through continued release of protease inhibitor, a growth factor, and nutritive elements that aid the biochemistry of epithelial regeneration. Phase 2 of this research proposes to optimize release of the active ingredients, test efficacy using a cell culture assay, and move to animal studies with the lead formulation. Evaluation parameters are provided for each step to validate progress.

SBIR

Phase II

2006

DOD

ARMY

Chemical Casualty Care: Wound Dressings Designed to Speed Wound Closure Following Debridement of Cutaneous Vesicant Injuries

Amount: $110,000 Topic: A05-131

QMT has technology in hand to develop a novel wound dressing that has potential to greatly enhance the rate of healing for debrided vesicant agent injuries, as well as related chronic wounds. The matrix of the dressing is based on a polyelectrolyte complex that consists of a highly absorbent anionic material (carboxymethyl cellulose, CMC) that is treated with a synthetic cationic polymer to enhance structural cohesion and to provide sustained release of a broad spectrum antibiotic (doxycycline) that also acts as an general inhibitor of metalloproteinases (MMPs and TNFa converting enzyme), which will reduce inflammation and proteases that retard wound healing. The polyelectrolyte complex matrix material is engineered to conform to the wound surface, and together with the backing layer of low moisture vapor penetration film, provide a moist wound healing environment. Further features of the dressing include controlled release of a growth factor (EGF) and antioxidants (vitamin C and E) that have been demonstrated to enhance the rate of wound healing. All ingredients are known to be robust, and the proposed dressing should have an indefinite shelf life without need for special storage conditions.

SBIR

Phase I

2005

DOD

ARMY