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LUCERNA INC
http://www.lucernatechnologies.com
UEI: J3MWGA6WFCG3
# of Employees: 7
HUBZone Owned: No
Socially and Economically Disadvantaged: No
Woman Owned: No
Award Charts
Award Listing
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Fluorescent IRE sensor for synucleinopathy drug discovery
Amount: $853,817.00ABSTRACT The goal of this Phase II proposal is to advance synucleinopathy disease drug discovery by validating a high- throughput screening (HTS)-ready assay and establish a RNA structure sensor platf ...
SBIRPhase II2022Department of Health and Human Services National Institutes of Health -
Cell-based assay directly monitoring viral polymerase activity for drug discovery.
Amount: $224,323.00Project Abstract/Summary Our goal is to develop a new cell-based HTS platform that can be used to improve antiviral drug discovery. Infection by Dengue virus causes ~100 million illnesses annually, wi ...
SBIRPhase I2020Department of Health and Human Services National Institutes of Health -
Cell-based assay directly monitoring RNA Polymerase I activity for cancer drug discovery
Amount: $223,700.00Project Abstract/Summary Cancer is the second leading cause of death in the US, with ~600k cancer related deaths and 1.7 million new cases of cancer diagnosis expected in 2019. There have been signifi ...
SBIRPhase I2020Department of Health and Human Services National Institutes of Health -
TOPIC 356: FLUOROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION
Amount: $1,480,983.00Circular RNAscircRNAsare a novel class of modified RNAs that are an abundant component of the epitranscriptomePutative functions of circRNAsinclude miRNA sequestrationRNA binding protein scaffoldingmR ...
SBIRPhase II2019Department of Health and Human Services National Institutes of Health -
New high-throughput screening technologies to improve cannabinoid production in yeast.
Amount: $224,928.00SUMMARY Natural products derived from plants have played crucial roles in the treatments of many diseases throughout historyHoweverscarce natural sources and complex chemical synthesis have limited re ...
SBIRPhase I2019Department of Health and Human Services National Institutes of Health -
TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION
Amount: $49,973.00Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein s ...
SBIRPhase I2018Department of Health and Human Services National Institutes of Health -
Fluorescent IRE sensor for PD drug discovery
Amount: $221,896.00SUMMARY Parkinsonandapos s diseasePDis a debilitating neurodegenerative disease that affects aboutof the population over the age ofThe pathological hallmark of PD is the presence of intracellular prot ...
SBIRPhase I2018Department of Health and Human Services National Institutes of Health -
Splice sensors for cancer drug discovery
Amount: $1,491,344.00SUMMARY: RNA splicing plays a central role in the generation of proteome diversity and in gene regulation. Splicing impacts vital cellular processes, such as cell-fate and differentiation, acquisition ...
SBIRPhase II2018Department of Health and Human Services National Institutes of Health -
Cell-based viral helicase assay for dengue drug discovery
Amount: $224,475.00SUMMARY The dengue virusDENVis a mosquito borne RNA virus that is responsible for overmillion infections a yearWhile dengue fever is mostly self limitingsevere dengue diseases are the leading causes o ...
SBIRPhase I2018Department of Health and Human Services National Institutes of Health -
Assay Classifier Engine (ACE) for enhancing splice sensor assay performance
Amount: $224,925.00SUMMARYThe goal of this proposal is to improve the sensitivity and specificity of the Spinach based splice sensor platform by developing a novel multiprobeMPassay design and a companion machine learni ...
SBIRPhase I2018Department of Health and Human Services National Institutes of Health
