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MICROBIOTIX, INC.

Company Information
Address
1 Innovation Dr
Worcester, MA 01605-4307
United States



Information

UEI: SCNKBDM341T1

# of Employees: N/A


Ownership Information

HUBZone Owned: No

Socially and Economically Disadvantaged: No

Woman Owned: No



Award Charts




Award Listing

  1. Discovery of Bunyaviral Endonuclease Inhibitors for Antiviral Therapy

    Amount: $296,536.00

    Abstract Segmented negative-sense, single-stranded RNA viruses (sNSVs), which include bunyaviruses, are causative agents of human diseases. Rift Valley Fever Virus (RVFV), a bunyavirus, causes hemorrh ...

    STTRPhase I2022Department of Health and Human Services National Institutes of Health
  2. Type 3 secretion system inhibitors to treat Pseudomonas aeruginosa keratitis

    Amount: $300,156.00

    Contact lens-associated bacterial keratitis is a serious infection of the eye that can result in blindness if treatment is not effective. The opportunistic Gram-negative pathogen Pseudomonas aeruginos ...

    SBIRPhase I2022Department of Health and Human Services National Institutes of Health
  3. Screening for rAAV transduction enhancers

    Amount: $1,986,668.00

    ABSTRACTRecombinant adeno-associated virus (rAAV) is an established vector for gene therapy and vaccines with the potential to radically change the face of modern healthcare. Although extremely promis ...

    SBIRPhase II2021Department of Health and Human Services National Institutes of Health
  4. Development of Filociclovir for the Treatment of Ocular Adenoviral Infections and Keratoconjunctivitis

    Amount: $1,462,324.00

    Project Summary/AbstractThe long-term goal of this project, to develop filociclovir (FCV) for the safe and effective treatment of human ocular adenovirus (AdV) infections, especially AdV-related epide ...

    SBIRPhase II2021Department of Health and Human Services National Institutes of Health
  5. Discovery of Enterovirus D68 2A protease inhibitors for antiviral therapy

    Amount: $600,000.00

    Abstract Enterovirus D68 (EV-D68), a highly contagious non-polio enterovirus, caused the 2014 outbreak affecting thousands of people in multiple countries, including the US, Canada and Europe. Histori ...

    SBIRPhase I2020Department of Health and Human Services National Institutes of Health
  6. Inhibitors of T3SS translocon assembly to combat multi-drug resistant P. aeruginosa

    Amount: $599,449.00

    Abstract Pseudomonas aeruginosa (PA) is the bacterium most frequently isolated from the respiratory tract of ICU pa- tients in the US and is a major cause of pneumonia in intubated patients. Furthermo ...

    STTRPhase I2020Department of Health and Human Services National Institutes of Health
  7. Development of a New Class of Hepatitis B Virus Inhibitors that Induce a Novel Defective Nucleocapsid Phenotype

    Amount: $596,806.00

    Summary: Hepatitis B virus (HBV) is a small DNA virus that chronically infects 240 million people worldwide, resulting in over 650 thousand deaths annually. HBV-induced fatalities typically result fro ...

    SBIRPhase I2020Department of Health and Human Services National Institutes of Health
  8. Development of a novel broad-spectrum inhibitor of non-polio enteroviruses associated with acute flaccid myelitis

    Amount: $585,191.00

    Development of a novel broad-spectrum inhibitor of non-polio enteroviruses associated with acute flaccid myelitis Summary: Despite the eradication of poliovirus in the US and Europe more than 20 years ...

    SBIRPhase I2020Department of Health and Human Services National Institutes of Health
  9. Novel Plasmodial Surface Anion Channel Inhibitors as Antimalarial Drugs

    Amount: $2,974,411.00

    Summary/Abstract The overall objective of this project is to develop new, potent, selective antimalarials that act through a novel mechanism of blocking the plasmodial surface anion channel (PSAC), a ...

    SBIRPhase II2019Department of Health and Human Services National Institutes of Health
  10. Optimization of novel pyranopyridine efflux pump inhibitors

    Amount: $2,968,757.00

    ABSTRACT The inadequacy of current treatment options to cure infections caused by MDR Gram-negative pathogens results in high rates of morbidity and mortality along with their concomitant treatment co ...

    SBIRPhase II2019Department of Health and Human Services National Institutes of Health
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