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NAPROGENIX, INC.

Company Information
Address
UK-ASTECC 145 Graham Avenue
Lexington, KY 40506-0001
United States


http://www.naprogenix.com

Information

UEI: N1NBJ43SQGX7

# of Employees: 8


Ownership Information

HUBZone Owned: No

Socially and Economically Disadvantaged: No

Woman Owned: No



Award Charts




Award Listing

  1. Development of JR-220 (4-Chlorobenzylidenamino-guanidine hydrochloride) as a medication for alcohol dependence

    Amount: $3,415,022.00

    Abstract Alcohol dependence affects at least 4% of the US population, with a financial cost in excess of $100Bn. Prevention of relapse in patients attempting to reduce alcohol consumption is a major t ...

    SBIRPhase II2021Department of Health and Human Services National Institutes of Health
  2. Mimicking synuclein toxicity in plant cells to identify novel neuroprotective leads

    Amount: $1,859,037.00

    Abstract A general mechanism for neurodegeneration, including Parkinson's disease and Alzheimer's dementia, is the breakdown and subsequent aggregation of misfolded neuronal proteins. In the “synucl ...

    SBIRPhase II2020Department of Health and Human Services National Institutes of Health
  3. Novel modulators of the dopamine transporter for alcohol and nicotine use disorders

    Amount: $2,972,532.00

    Abstract Substance use disorders (SUDs) are at epidemic levels in the US [Mack et al 2017] and this has accelerated efforts to find effective pharmacotherapies. All SUDs are associated with increased ...

    SBIRPhase II2020Department of Health and Human Services National Institutes of Health
  4. Mimicking synuclein toxicity in plant cells to identify novel neuroprotective leads

    Amount: $231,474.00

    Abstract Alpha synucleinASYNis believed to play an important role in the pathology of several neurodegenerative conditionsincluding some forms of Parkinsonandapos s diseaseDementia with Lewy Bodiesand ...

    SBIRPhase I2018Department of Health and Human Services National Institutes of Health
  5. Harvesting specific plant metabolites from hairy root cultures using magnetized nanoparticles

    Amount: $1,029,017.00

    AbstractPlant cell cultures are becoming a commercially valuable source of pharmaceuticalsparticularly those that are too complex for economical chemical synthesisFor example Phyton Biotechin Germanyh ...

    SBIRPhase II2017Department of Health and Human Services National Institutes of Health
  6. Development of JR-220 (4-Chlorobenzylidenamino-guanidine hydrochloride) as a medication for alcohol dependence

    Amount: $1,467,135.00

    Abstract Alcohol dependence affects at leastof the US populationwith a financial cost in excess of $BnPrevention of relapse in patients attempting to reduce alcohol consumption is a major therapeutic ...

    SBIRPhase I2017Department of Health and Human Services National Institutes of Health
  7. Mutant transgenic plant cells as a novel source of drugs

    Amount: $1,050,389.00

    Abstract of administrative supplement The original objective was to use a novel plant biotechnologytarget directed evolutionto produce novel inhibitors of the human dopamine transporterDATas leads for ...

    SBIRPhase II2016Department of Health and Human Services National Institutes of Health
  8. IGF OT IGF POTENTIAL COMMERCIALIZATION OF PROPRIETARY COMPOUND JR

    Amount: $285,767.00

    alcohol

    SBIRPhase II2016Department of Health and Human Services National Institutes of Health
  9. Novel flavonoids as anti-inflammatory agents in alcoholism

    Amount: $150,900.00

    DESCRIPTION (provided by applicant): Flavonoids are ubiquitous secondary metabolites in plants with many known health benefits, which are mostly ascribed to their potent anti-oxidant activity. Howev ...

    SBIRPhase I2014Department of Health and Human Services National Institutes of Health
  10. Harvesting specific plant metabolites from hairy root cultures using magnetized n

    Amount: $189,844.00

    DESCRIPTION: Plants produce a wide variety of valuable bioactive metabolites, but these are commonly present in low concentrations in the wild-type plant. This makes the separation and purification o ...

    STTRPhase I2014Department of Health and Human Services National Institutes of Health
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