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Yecuris Corporation
UEI: N/A
# of Employees: 9
HUBZone Owned: No
Socially and Economically Disadvantaged: No
Woman Owned: No
Award Charts
Award Listing
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Chimeric Rats for Liver Humanization
Amount: $243,211.00DESCRIPTION (provided by applicant): Yecuris has developed an in vivo genetic selection system (the FRG KO mouse) that permits extensive humanization of murine liver by transplantation with human he ...
SBIRPhase I2014Department of Health and Human Services National Institutes of Health -
Double Humanization of Liver and Blood in Mice
Amount: $230,670.00DESCRIPTION (provided by applicant): Chimeric mice with highly humanized livers have multiple potential applications in research and preclinical drug development both in the academic and commercial se ...
SBIRPhase I2012Department of Health and Human Services National Institutes of Health -
FAH-Deficient Pigs
Amount: $212,374.00DESCRIPTION (provided by applicant): Translational research in the field of liver disease has been limited by a shortage of large animal models, which in turn has limited development of new therapies ...
STTRPhase I2011Department of Health and Human Services National Institutes of Health -
In Vivo Expansion of Human Hepatocytes in FRG Mice
Amount: $773,666.00DESCRIPTION (provided by applicant): The FDA requires the use of human hepatocytes for preclinical drug testing by pharmaceutical researchers, but unfortunately the supply of these cells is severely l ...
STTRPhase II2011Department of Health and Human Services National Institutes of Health -
In vivo expansion of human hepatocytes in Fah-/-Rag-/-Il2rg-/- mice
Amount: $325,496.00DESCRIPTION (provided by applicant): The liver is the site of many metabolic processes, including metabolism of xenobiotics such as pharmaceutical compounds. Drug metabolism is highly species specific ...
STTRPhase I2010Department of Health and Human Services National Institutes of Health