Award Data

Municipal Solid Waste (MSW) is a huge untapped renewable feedstock resource to produce hydrogen through gasification. Currently, the utilization MSW for hydrogen production is not realized due to the presence of chlorine that causes degradation of gasifier components and formation of pollutants during gasification. This proposed technology has the potential to remove chlorine and produce a consist ...

High-quality, defect free, and consistent thickness Proton Exchange Membrane (PEM) films are required to ensure maximum efficiency and longevity over the life of hydrogen fuel cells or electrolyzers utilizing this technology. The current technologies of PEM film Quality Assurance (QA) and defect detection rely on human inspection, which can be subjective and labor intensive, or measurement technol ...

Project SummaryAccumulated snowpack is a major source of water throughout the United States. Accuratelymonitoring snow on the northern plains is a significant need for streamflow forecasting andreservoir management. This has been demonstrated by the US Army Corp of Engineersestablishment of the Upper Missouri River Basin Plains Snow and Soil Moisture MonitoringNetwork. The availability of a low-co ...

Project Summary The goal of this Fast Track STTR project is to determine proof-of-principle and efficacy of a novel blood brain barrier (BBB) penetrating therapeutic nanoparticle for the potential treatment of otherwise intractable brain tumors like glioblastoma multiforme (GBM). This project seeks to demonstrate that novel, targetable nanoparticles can delivery therapeutic substances to human bra ...

The goal of this project is to develop a treatment booth with technology that allows opioid treatment programs to remotely dispense, either methadone or buprenorphine, under medical observation through telemedicine to a patient in a treatment booth. We believe that robotic automation is the ideal application to perform the same mechanical functions of the nurse at the dosing window. Specifically, ...

Abstract Pharmacogenomics, the study of how an individual's genetic makeup affects their response to drugs, has undergone rapid advancements. This has occurred alongside a decrease in the cost of genotyping technology, making implementation of pharmacogenomics into clinical practice increasingly feasible. Personalized medicine leveraging pharmacogenomics is gaining momentum to optimize drug choice ...

Project Summary / Abstract DermaXon's project goal is to develop efficacious, substrate-based, selective inhibitors of CYP26s, the enzymes responsible for the metabolism of all-trans retinoic acid (atRA) in the epidermis, as an oral treatment for severe recalcitrant acne. This approach will provide an improved acne therapeutic without the adverse effects associated with currently marketed retinoid ...

This Phase I SBIR will lead to the development of a bandwidth tailored pump source for high purity photon pair generation. Spontaneous parametric down conversion can be used to generate high purity photon pairs at wavelengths of interest to NASA and the broader scientific community. However, these sources are highly dependent on pulsed pump laser parameters. Traditional pulsed laser sources are la ...

This Phase II project aims to prototype a novel technology that can advance the state-of-the-art in high performance space computing.nbsp; The base computer technology, called ldquo;RadPCrdquo;, brings together a suite of fault recovery mechanisms that enable Commercial-off-the-Shelf (COTS) Field Programmable Gate Arrays (FPGAs) to operate reliably in the presence of space radiation that causes si ...

This project proposes a coprocessor companion to future radiation-hardened processors that can boost performance using commercial Field Programmable Gate Arrays (FPGA). nbsp;This project will investigate the feasibility of using dynamically reconfigurable coprocessing circuitry within a proven fault-tolerant architecture known as RadPC.nbsp; The RadPC architecture has been matured through NASA-fun ...