Award Data

7. PROJECT SUMMARY Breast cancer is the most common cancer worldwide and the most common cancer diagnosed in American women. While there has been good progress regarding detection and treatment methods, breast cancer remains the primary cause of death from malignant tumors. Hence, there is a critical need for the development of novel predictive and prognostic factors. Risk assessments are currentl ...

Prapela proposes to complete the development of and then establish the safety, efficacy, and clinical risk/benefit of a novel hospital incubator pad that will provide a complementary treatment and the first improvement in the clinical management of apnea of prematurity (AOP) in over 20 years. Defined as cessation of breathing for 20 seconds or longer or a shorter pause accompanied by hypoxemia, AO ...

PROJECT SUMMARY The research project outlined in this Fast track SBIR submission will develop the RAE cHealth platform into a tool to address digital inequities and support peer-based collaborative recovery for individuals with substance use disorder. In this proposal, the investigators intend to develop and deploy the RAE cHealth system- consisting of a wearable sensor and a smartphone app. RAE c ...

PROJECT SUMMARY The research project outlined in this Fast track SBIR submission will develop the RAE cHealth platform into a tool to address digital inequities and support peer-based collaborative recovery for individuals with substance use disorder. In this proposal, the investigators intend to develop and deploy the RAE cHealth system- consisting of a wearable sensor and a smartphone app. RAE c ...

Project Summary/Abstract Maternal use and addiction to opioids has resulted in an unprecedented rise in drug withdrawal complications in newborns, known as neonatal opioid withdrawal syndrome (NOWS), also referred to as neonatal abstinence syndrome (NAS). Between 2004 and 2016, NOWS admissions increased more than fourfold, with an average hospital stay nearly 3.2 times longer (15.9 hospital days c ...

PROJECT SUMMARY The research project outlined in this SBIR submission will develop the Realize, Analyze, Engage (RAE) platform into a tool to promote sustained recovery in individuals receiving treatment for substance use disorder. In this proposal, the investigators intend to deploy the RAE system- consisting of a wearable sensor, a smartphone app, and a clinical portal- to provide individuals in ...

PROJECT SUMMARY/ABSTRACT There are an estimated 23.7 million people who are blind or visually-impaired (BVI) in the U.S. and 285 million globally. Of this population, 30% do not travel independently outside of their home, only ~11% have a bachelor’s degree, and more than 70% are unemployed. The goal of this SBIR effort is to develop a novel system, which performs principled down-sampling and tra ...

! PROJECT SUMMARY The research project outlined in this SBIR submission will develop the Realize, Analyze, Engage (RAE) platform into a tool to promote sustained recovery in individuals receiving treatment for substance use disorder. In this proposal, the investigators intend to deploy the RAE system- consisting of a wearable sensor, a smartphone app, and a clinical portal- to provide individuals ...

PROJECT SUMMARY ABSTRACT Hip fracture is one of the most serious fall related injuries in older adultshas a high rate of mortality and higher rate of disabilityThe incidence of hip fractures continues to increase as older adults become a larger proportion of the U SpopulationWithin one year post hip injuryof elderly die andof community dwellers are placed in nursing homesAccordinglyhip injury prev ...

Project Summary While nucleic acid therapeutics have shown promise in rodent and nonhuman primate models of CNS diseasesall double blind clinical trials to date have failedOne likely explanation for this failure is poor therapeutic distribution in targeted brain regionsFor examplepost mortem studies of patients with Parkinsonandapos s Disease receiving intraparenchymal injections of AAV NTN demons ...