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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Physics-Based Identification, Modeling and Management Infrastructure of Aeroelastic Limit-Cycle Oscillations

    SBC: Advanced Dynamics, Inc.            Topic: AF07T006

    The proposed research program aims to develop a physics-based identification, modeling and management infrastructure for aeroelastic limit-cycle oscillations. This infrastructure will be built upon high fidelity state-of-the-art theoretical/computational methods as validated and verified by available experimental data bases, and will include (1) rapid flutter boundary determination for a wide ran ...

    STTR Phase I 2007 Department of DefenseAir Force
  2. Transdermal Cannabidiol Delivery for Alcohol-Induced Neurodegeneration

    SBC: ALLTRANZ, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Treatment of alcohol use disorders (AUDs), commonly referred to as alcoholism, has been hampered by alcohol's promiscuous pharmacological effects and the complex etiology of addiction. People drink in excess for a variety of reasons, and an approach that targets more of these reasons will have greater commercial success than an approach that only targets a sole ...

    STTR Phase I 2007 Department of Health and Human Services
  3. ApoFasL: a Novel Immunotherapeutic for T1D

    SBC: APOIMMUNE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Type 1 Diabetes (T1D) is an autoimmune disease that targets insulin secreting pancreatic beta cells for destruction and remains a major cause of morbidity and mortality in over 1% of the population worldwide. Although insulin therapy and islet transplantation are currently the most effective treatments, both of these approaches suffer from major limitations inc ...

    SBIR Phase I 2007 Department of Health and Human Services
  4. ApoVax-SVN as a Novel Vaccine for Cancer Immunotherapy

    SBC: APOIMMUNE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): The main objective of this proposal is to develop a novel cancer vaccine, ApoVax-SVN(tm) based on the use of a proprietary costimulatory chimeric ligand, 4-1BBL, designed to specifically deliver survivin, a tumor associated antigen (TAA) to professional antigen-presenting cells (APCs) and activate them for the generation of an effective anti-tumor immune respon ...

    STTR Phase I 2007 Department of Health and Human Services
  5. ApoVax104-HPV as a Novel Vaccine for Cervical Cancer

    SBC: APOIMMUNE, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Various cancer vaccines based on tumor associated antigens (TAAs) or tumor specific antigens (TSAs) have shown efficacy in preclinical models. However, their therapeutic efficacies have been rather limited in clinical trial settings. Although the reason for clinical inefficacy for these vaccines is not known, the lack of an adjuvant with potent immunostimulato ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. Stimulation Augmented Recumbent Stepper for Stroke Rehabilitation

    SBC: CUSTOMKYNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Among the most significant goals of therapeutic exercise following stroke are maintaining strength and endurance of paretic muscles and aiding in restoration of functional use of the affected limbs. One relatively new and promising device that may address these aims is the NuStep TRS4000 recumbent cross trainer, which provides a coupled reciprocal leg/arm exte ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. Adaptive High Intensity Electrical Stimulation for Post-Surgical Rehabilitation

    SBC: CUSTOMKYNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Recovery of quadriceps muscle force following post-surgical knee immobilization is a significant therapeutic aim which is associated with quality of gait and the ability to perform activities of daily living. Several st udies from various research groups have shown that neuromuscular electrical stimulation (NMES), used in conjunction with a comprehensive post-s ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. STTR Phase I: A real-time Collaborative Click Fraud Detection and Prevention System

    SBC: Hosting.com            Topic: IT

    This Small Business Technology Transfer (STTR) Phase I project will provide a commercial solution to click fraud identification and prevention. The current existing solutions can not detect the so-called software click. This STTR project proposes a real time collaborative click fraud detection and prevention system to detect these software clicks. The approach draws on data mining techniques for ...

    STTR Phase I 2007 National Science Foundation
  9. SBIR Phase I: The Media Fusion Project: A Distributed Architecture for Mega-Pixel Displays

    SBC: Mersive Technologies, LLC            Topic: EO

    This Small Business Innovation Research Phase I project will develop an architecture to support the management and display of media on a new class of emerging displays. The proposed architecture is a new approach to supporting displays with the ability to 1) reconfigure themselves as different display components (projectors) are repositioned and 2) scale to potentially hundreds of millions of pixe ...

    SBIR Phase I 2007 National Science Foundation
  10. Transgenic plant cells as a source of hepatoprotective drugs

    SBC: NAPROGENIX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alcoholic liver damage (ALD) is among the top ten causes of death in the USA, but existing therapeutic interventions are relatively ineffective. Hepatocytes are susceptible to damage probably because they have a high level of alcohol dehydrogenase (ADH) which metabolizes alcohol to form acetaldehyde and reactive oxygen species (ROS), which are both cytotoxic. C ...

    STTR Phase II 2007 Department of Health and Human Services

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