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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. BioSphincter to Treat Fecal Incontinence. Phase 1/2 Clinical Trial. SBIR Phase IIB

    SBC: CELLF-BIO, LLC            Topic: 300

    Project Summary AbstractFecal incontinenceFIthe involuntary soiling of various amounts of liquid and solid stoolis often devastating from a socialpsychologicaland hygiene perspectiveMen and women suffer from FI equally with a range ofin people agedyearsThe prevalence increases to overin people older thanyearsFI may result from an isolated or combined loss of smooth muscle functionIASskeletal muscl ...

    SBIR Phase II 2018 Department of Health and Human Services
  2. Living with CKD: An E-Learning Platform for Adolescents with CKD about the Disease and its Management

    SBC: 3-C Institute for Social Development, Inc.            Topic: 300

    Abstract Chronic kidney diseaseCKDis a progressive conditioncharacterized by an irreversible deterioration of renal function that gradually progresses to end stage renal diseaserequiring dialysis or kidney transplantCKD and its co morbiditiese ghypertensionanemiaacidosisand metabolic bone diseaserequire strict treatment adherence to halt progression and improve outcomesUnfortunatelythe majority of ...

    SBIR Phase II 2018 Department of Health and Human Services
  3. Point-of-care device to identify patients at risk for preeclampsia

    SBC: AFFINERGY, LLC            Topic: N

    Although international trends for maternal mortality have shown an overall declinematernal mortality rates in the United States have increased by rtsinceOne of the leading causes for this increase is preeclampsiaa complication of pregnancy characterized by elevated blood pressureproteinuriaand endothelial dysfunction involving multiple organ systemsWorldwidepreeclampsia is one of the leading cause ...

    SBIR Phase II 2018 Department of Health and Human Services
  4. CometChip: Development of a high throughput DNA damage assay in hepatocytes

    SBC: INTEGRATED LABORATORY SYSTEMS, INCORPORATED            Topic: NIEHS

    An estimatedanimals are used in toxicology safety assessments to meet all regulatory requirements with testing spanningtoyrs and exceeding $million dollarsThere is a critical need to reduce reliance on animal testing and to develop highly predictive human based biological models for safety assessmentsReplacement of traditional animal toxicity tests for toxicology safety assessments with alternativ ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Increased sensitivity of minimal residual disease monitoring using peripheral blood in pediatric patients with acute lymphoblastic leukemia

    SBC: BIOFLUIDICA, INC.            Topic: 102

    Abstract Acute lymphoblastic leukemiaALLis the most common malignant disease in childhood and accounts for approximatelyof all cancers diagnosed before the age ofyearsThe primary cause of death for ALL patients is disease relapseThereforemonitoring for minimal residual diseaseMRDis considered the most powerful predictor of outcome in acute leukemiasincluding B type acute lymphoblastic leukemiaB AL ...

    SBIR Phase I 2018 Department of Health and Human Services
  6. SBIR Phase II: Online Game to Assess and Improve Behavioral Readiness and Social Emotional Skills for Students in Kindergarten and First Grades

    SBC: Personalized Learning Games Inc            Topic: EA

    This SBIR Phase II project aims to create and test a game-based intelligent tutoring system that both assesses and improves the behavioral readiness and social emotional skills of Kindergarten and 1st grade students. Research has shown that early intervention for children with social skill deficiencies is critical for success in the classroom and success in life. Children from vulnerable, underser ...

    SBIR Phase II 2019 National Science Foundation
  7. Advanced Indoor Navigation Aid for Blind and Visually-Impaired Individuals in Unfamiliar Spaces

    SBC: Vortant Technologies, LLC.            Topic: N

    Project Summary Abstract Confusionbeing lostand losing track of oneandapos s orientation within large or unfamiliar indoor spacesthese are some of the biggest challenges facing people with visual disabilitiesSince GPS typically doesnandapos t work indoorsand isnandapos t fine grained enough anywayindividuals who cannot readily access visual information are at a significant disadvantageand many bli ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Dermal Medical Countermeasures for Chemical Weapons Exposure

    SBC: Zymeron Corporation            Topic: CBD161003

    The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...

    SBIR Phase I 2017 Department of DefenseOffice for Chemical and Biological Defense
  9. Dermal Medical Countermeasures for Chemical Weapons Exposure

    SBC: Zymeron Corporation            Topic: CBD161003

    The skin is the first line of defense against chemical warfare agents including nerve agents and toxic industrial chemicals, providing a possible barrier or delay to systemic distribution. Some chemicals also can act directly on the skin including the vesicants sulfur mustard and lewisite. Early and rapid skin decontamination is extremely important following exposure to CWAs and TICs because it de ...

    SBIR Phase II 2018 Department of DefenseOffice for Chemical and Biological Defense
  10. A crosslinked cartilage-derived matrix for cartilage tissue engineering

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    Abstract OsteoarthritisOAremains a significant source of significant pain and disabilityaffecting overmillion adults with an economic burden of over $billion per year to the USJoint replacement is a well established procedurebut its finite life span makes this treatment unacceptable for younger or more active individualswho often require additional revision surgeries as they ageBoth complicated re ...

    SBIR Phase II 2017 Department of Health and Human Services

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