Award Data

DESCRIPTION provided by applicant Prostheses reduce the incidence of contralateral overuse syndrome in upper limb amputees by encouraging balanced bimanual limb usage Benefits include reduced pain and muscular atrophy increased productivity and self reliance improved self image a sense of well being and increased social acceptance Body powered prostheses are used extensively in the Uni ...

Project SummaryAbstract There is growing need of high throughput analytical platforms to study interactions of cell surface glycans and glycan binding proteinsWe propose here to develop aKglycan array to facilitate functional glycomics researchTwo hurdles for development of a comprehensive glycan array arelack of a sensitive glycan array substrate enabling multivalent binding eventsandlack of a co ...

ABSTRACT Significance Electronic prescribing is now widely adopted by US healthcare systems but clinical functionality of e prescribing falls short in the realm of pediatrics Medication prescribing is intrinsically more complex for pediatric patients due to weight based dosing the lack of widely adopted medication formulation recipes inconsistent off label ...

DESCRIPTION provided by applicant The goal of this project is to develop a very low cost whole head neonatal MEG system that can adapt to the shape and size of the head Clinically there is a longstanding need for a technology that can aid in the diagnosis and prognosis of babies with brain dysfunction due to intrauterine and postnatal central nervous system insults which may result in menta ...

DESCRIPTION (provided by applicant): Nearly 12 million wounds are treated in U.S. emergency departments every year. Skin wounds such as severe burns, large trauma wounds, or non-healing/chronic wounds that are too extensive or complex to close by natural healing are often reconstructed using autologous skin grafts. Although autologous skin grafts are currently the gold standard in complex wound re ...

Inhibikase Therapeutics is a clinical stagebiopharmaceutical company that has developed a hosttargeted mechanism of action to treat AIDS related and drug induced progressive multifocal leukoencephalopathyPMLPML is a demyelinating disease of the central nervous system and was rarely seen clinically until the era of the HIV epidemic began in the midsDuring the height of the epidemicthe rate of PML o ...

PROJECT SUMMARY ABSTRACT The recent acceleration in incidence and intensity of human disease caused by Zika virusZIKVinfection has prompted an international outcry for safe and effective countermeasuresCurrently protection against mosquito bites and vector control are the only measures available to prevent ZIKV infectionsA vaccine is urgently neededThe studies proposed here build on previous work ...

Abstract Summary JANUS Research Group proposes to develop a mixed reality technology solution that will provide individual and small group training that makes use of mobile platforms such as smartphones and tablets to support e learning of health and safety issues related to hazardous radiological material for first responders Our proposed approach leverages the capabilities of modern mobile de ...

Parkinson s DiseasePDis a progressive neurodegenerative disorder that affectsmillion patient in the U Sannually andtomillion people worldwidePD is characterized by disorders of movementwhich are caused by the progressive loss of dopamine neurons in the substantia nigra pars compactaSNpcand autonomic dysfunctionanxietydepressionsleep disorders and cognitive impairment that are due to the degenerati ...

Significance Lung cancer is the leading cause of cancer deaths with over new diagnoses annually Survival rate of lung cancer patients is correlated with the extent of lymph node metastasis Standard care includes chemotherapy radiation and or surgery Cisplatin is a first line chemotherapy for lung cancer but systemic intravenous IV delivery is confounded by various toxicities rena ...