Award Data

WE WILL DEVELOP A BIODEGRADABLE WOUND TREATMENT THAT CAN BE AEROSOLIZED DIRECTLY ONTO A WOUND SURFACE. IT WILL FORM A TOUGH, FLEXIBLE FILM THAT WILL SEAL THE WOUND AND PROVIDE FOR PROPER WATER LEVELS AT THE WOUND SURFACE. AN ANTIBIOTIC WILL BE INCORPORATED INTO THE BIODEGRADABLE POLYMER AND WILL BE SLOWLY RELEASED INTO THE WOUND BOTH TO ELIMINATE EXISTING INFECTION AND TO PREVENT LATER INFECTION. ...

Electron-ion colliders (EICs) are the best microscopes for studying the structure of nuclear matter, particularly the nature and origin of spin in nuclei. To be effective, such machines require electron and ion beams with polarizations as high as 80%. Comprehensive end-to-end simulations to study the spin dynamics and optimize the beam polarization require exorbitant computational effort. We will ...

Project SummaryAbstract There is growing need of high throughput analytical platforms to study interactions of cell surface glycans and glycan binding proteinsWe propose here to develop aKglycan array to facilitate functional glycomics researchTwo hurdles for development of a comprehensive glycan array arelack of a sensitive glycan array substrate enabling multivalent binding eventsandlack of a co ...

DESCRIPTION (provided by applicant): Apeliotus Technologies proposes to develop a new clinical trial endpoint for age-related macular degeneration (AMD) based on dark adaptation. A major challenge in attacking AMD is the lack of adequate clinical trial endpoints. Visual acuity is currently the only accepted functional endpoint; however it is minimally impacted until the late stages of the disease ...

ABSTRACT Significance Electronic prescribing is now widely adopted by US healthcare systems but clinical functionality of e prescribing falls short in the realm of pediatrics Medication prescribing is intrinsically more complex for pediatric patients due to weight based dosing the lack of widely adopted medication formulation recipes inconsistent off label ...

THE HARD AND SOFT X-RAY SIGNAL RESPONSES TO A SAWTOOTH CRASHARE BEING USED TO MEASURE THE ENERGETIC ELECTRON DIFFUSION COEFFICIENT, D, AND THE THERMAL ELECTRON HEAT CONDUCTIVITY, E, SIMULTANEOUSLY UNDER IDENTICAL PLASMA CONDITIONS. PHASE I EMPLOYS A REPRESENTATIVE SET OF SOFT AND HARD X-RAY SAWTOOTH OSCILLATIONS FROM THE TEXAS EXPERIMENTAL TOKAMAK (TEXT) TO DEVELOP THE MATHEMATICAL MODELING NECESS ...

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DESCRIPTION (provided by applicant): Although the influenza vaccine has been used for over 60 years, the current vaccination strategy against influenza A and B viruses is vulnerable to the unanticipated emergence of epidemic strains that are poorly matched by the vaccine. Epidemics of seasonal influenza and increased circulation of avian influenza virus subtypes constitute a significant healthcar ...

The DOE is interested in the development of efficient tidal turbine systems to help meet the future energy needs of the United States. State-of-the-art tidal turbine systems feature composite tidal turbine blades. Unfortunately, composite materials possess questionable durability characteristics relevant to the marine environment (e.g., poor cavitation-erosion and impact-damage-resistance), whic ...

A need exists for advanced instrumentation neutron-flux mapping with in the reactor-core for the Transient REActor Test (TREAT) facility and Advanced Test Reactor (ATR) experiments supporting advanced nuclear material testing. In addition, many U.S. research reactors and industrial power nuclear-reactors would benefit from in-core neutron-flux monitoring. Here it is proposed to research advanced M ...