Award Data

The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase I project is to enable people who aspire to higher education and/or career opportunities to create a demonstrable portfolio of soft skills based on their lived experiences. Soft skills (e.g., problem-solving, teamwork, leadership, etc.) are as important as hard skills for individual success. However, current soft ...

The broader/commercial impacts of this Small Business Innovation Research (SBIR) Phase I project are to transform the way in which polymeric materials are developed. Adopting the most advanced artificial intelligence (AI) techniques, the proposed technology seeks to dramatically accelerate the exploration of new polymer formulations, efficiently and accurately discovering those with targeted perfo ...

The broader/commercial impact of this Small Business Innovation Research (SBIR) Phase II project will improve and accelerate the development of new chemicals, processes, and formulations in the pharmaceutical industry. By harnessing the power of machine learning (ML), this project aims to save time and resources by up to 95%, while reducing waste generation, thereby enhancing the commercial and so ...

This Small Business Innovation Research (SBIR) Phase II project produces compact optical frequency standards using state-of-the-art optical frequency metrology techniques adopted from national metrology institutes. Commercially, these devices will produce fundamentally accurate and stable optical frequencies in the form of laser light. End uses of these optical frequency standards include telecomm ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project relates to the creation of a digital twin, an interactive, 3-dimensional model of a real-world system, of complex industrial environments and assets. This digital twin provides infrastructure necessary for the application of virtual reality training and augmented reality live-guided procedure ...

Advances in spatial metabolomic analysis of tissue biopsies using MALDI-MSI now enable the identification of numerous biochemical pathways as signatures of specific histopathology features. However, the lack of reproducibility across experimental studies without a common internal standard limits the application of MALDIMSI for drug development. SygnaMap is developing MSI-DeepPath as an innovative ...

For this project, the team at Framergy, Inc. in partnership with Texas A&M University (TAMU), will analyze the feasibility of post-synthetic incorporation of metal-organic frameworks (MOFs) into polymer composites. This manufacturing method has the distinct advantage of eliminating the synthesis optimization that is often needed in in-situ growth methodologies, while also allowing for a higher de ...

Abstract Radiation induced keratopathy results in significant ocular surface disease, stem cell deficiency, vision loss, discomfort, and subsequent poor quality of life, affecting up to 23% of patients receiving radiation therapy for head and neck malignancies [1]. Studies have pointed out functional roles of corneal neurons and secretory cells of the lacrimal gland in the etiology of radiation in ...

Project Summary Abstract Cardiovascular Implantable Electronic Devices (CIEDs) like a Permanent Pacemaker or Implantable Defibrillator are implanted in over 3 million Americans, with the average age of implantation in the 60s, 40% ≥ 70 years old, and 28% ≥ 80 years old. When a patient presents to the Emergency Department (ED) with an unknown CIED, reprogramming of the device is often necessary ...

Summary AbstractHealthcare-associated infections (HAIs) are a threat to patient safety. Stopping the spread of HAIs requires prevention, surveillance, and outbreak investigations. Many hospitals are employing enhanced cleaning protocols, such UV disinfection, to their standard cleaning protocols, which when properly implemented have been shown to decrease the spread of HAIs. A significant challeng ...