Award Data

Currently, no commercial products exist for the repair of large injuries to muscle, particularly volumetric muscle loss (VML). In Phase I of this project, data demonstrated that keratin biomaterials can provide temporal release of growth factors while maintaining cell viability in vitro and in vivo. In Phase II, the biomaterial formulation was optimized for spatio-temporal delivery of cells and gr ...

The objective of this project is to develop, produce, and commercialize a liquid-tight, field-applicable, ocular patch for wound stabilization and treatment of the eye following a war-related injury to the ocular surface. The patch consists of a curved flexible silicone membrane (similar in size and shape to a contact lens) which has had (1) a novel bio-adhesive

Myoelectric prostheses can help service members and civilians that have acquired or congenital limb loss restore function. Substantial training is required to allow individuals to take full advantage of their prosthesis. Unfortunately, currently available training tools are expensive, non-motivating, manufacturer specific and typically must remain in the clinic. One goal of this proposal is t ...

Presently available pharmacotherapy for diabetes and pre-diabetes can be effective initially, but the natural history of these conditions typically features deterioration of blood sugar control over time and the accumulation of disability. Importantly, the current treatment approaches do not halt the underlying disease. Approved drugs for overweight and obesity have only limited efficacy and most ...

The objective of this proposal is to create an instrument to automatically measure the topology of the eye including corneal and scleral surfaces and create a highly accurate three dimensional model. The model is incorporated into two different ophthalmic programs for different applications. The first is a graphic interactive design tool to enable the doctor to create a computer simulated scleral ...

Although great strides have been made in the development of simulators for training technical and teamwork skills, substantially less progress has been made with regard to their assessment. Typically, skills and performance are assessed by an expert observer using a Likert-type rating scale with anchors ranging from low to high. However, such methods are extremely coarse, and often provide little ...

A lightweight, portable, robust system is proposed to detect and classify mild traumatic brain injuries rapidly in forward areas, based on on neuroscience and neurology-based algorithms and wearable computers of the newest generation.

US military medical personnel may be deployed to a variety of operational environments where their success saving lives depends on their ability to act quickly and effectively, both as individuals and as teams. Therefore, effective training must go beyond individual skills to include interactions among team members, and how those interactions transfer to operational environments. Currently, traine ...

Burn injuries, particularly those to the face, present a number of functional and psychological challenges that arise from scarring and related contracture. A major goal of trauma and burn surgeons is to prevent scarring and improve grafting technologies given the complexity of facial topography. This project seeks to optimize and finalize a prototype of a 3D printed keratin facemask capable of ...

Vivonics, Inc., together with clinical experts from the Mayo Clinic, are currently developing the Portable Multi-Modal Traumatic Brain Injury (PMT) monitor, a platform technology which will enable multiple neurological evaluations to be performed by a minimally trained person using a simple interface wired to a light-weight head-worn apparatus. During the Phase I period, the team successfully desi ...