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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Automated 3D quantitative analysis of dendritic spines imaged with light microsco

    SBC: MICROBRIGHTFIELD, INC.            Topic: NIMH

    DESCRIPTION provided by applicant In this Lab to Marketplace proposal we aim to develop the MBF SpineStudio software incorporating the innovative laboratory based NeuronStudio software created at the Mount Sinai School of Medicine Our SpineStudio software will enable automated detection reconstruction and morphological classification of the structural analysis of dendritic spines By creating this ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Digital Star HIV Prevention for Youth in Mental Health Treatment

    SBC: VIRTUALLY BETTER INC            Topic: 105

    DESCRIPTION provided by applicant Adolescents in mental health treatment are at greater risk for HIV and other STIs than their peers due to an earlier age of onset of sex less protected sex more sexual partners and more frequent substance use This greater risk is due to multiple factors including cognitive misperceptions affect dysregulation and less self efficacy The numerous adolescent ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. FASTCOUNT Next generation stereology platform for fast accurate D cell counting

    SBC: MICROBRIGHTFIELD, INC.            Topic: 101

    DESCRIPTION provided by applicant Stereologic cell counting has revolutionized the field of neuroscience over the last years and numerous studies highlighting the impact of stereologic cell counting in basic neuroscience and pharmaceutical and biotechnology research continue to be published A single study however may take months since investigators must decide by visual inspection whethe ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Anatomical Identification at the Microscope using the Brain Navigation System

    SBC: MICROBRIGHTFIELD, INC.            Topic: 101

    DESCRIPTION provided by applicant Microscopic analysis of histologic brain sections yields important information about the organization and composition of the nervous system particularly in modern studies focusing on neuro genomics transcriptomics proteomics and connectomics However identification of distinct brain regions in a section under study with the currently available tools pr ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. A Holographic Module for Multiphoton Microscopes in Neuroscience

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: 101

    DESCRIPTION provided by applicant Improving our understanding of the functional circuitry of the brain has important and manifold implications for our understanding of mental health as well as fields like consciousness and computing In the last decade optical techniques have arisen that allow both recording and control of targeted neurons for brain mapping and many of the best of these tech ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Novel Trap for Ticks and Fleas Incorporating a CO2 Generator

    SBC: TDA Research, Inc.            Topic: DHP13007

    Military personnel must be protected from diseases transmitted by ticks and fleas, including Lyme disease. Effective surveillance of tick and flea vectors is vital to determine the population present, whether they are carrying disease, and whether control campaigns are working. Unfortunately, current surveillance tools are ineffective. In Phase I TDA designed, prototyped, and tested a novel ti ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  7. Micro Patterned Intraocular Lens Membrane for Reducing Incidence of PCO

    SBC: Sharklet Technologies Inc.            Topic: N

    DESCRIPTION provided by applicant The exponential increase of diabetics and the elderly in the U S has more than tripled the number of cataract surgeries performed in just two decades As many as half of these surgeries will lead to posterior capsular opacification PCO which requires follow up Nd YAG laser capsulotomy surgery Without this additional procedure patients can suffer permanent ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Diagnosis of Bacterial Infections with Maltodexrins

    SBC: Microbial Medical, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant We present a new family of contrast agents based on targeting the maltodextrin transporter termed maltodextrin based imaging probes MDPs which are designed to image infections associated with implanted medical devices by fluorescent imaging The chemical structure of an MDP is composed of maltodextrins conjugated to a fluorescent dye MDPs have the potentia ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Single-Use Delivery Device for Bioabsorbable Fasteners

    SBC: OPUS KSD, INC.            Topic: 100

    DESCRIPTION provided by applicant The surgeonandapos s choice of method for closing incisions is becoming increasingly problematic Metal surgical staples are unacceptable for Minimally Invasive Surgery MIS procedures currently percent of surgeries in the US and are out of favor in traditional procedures due to complications and the cost of staple removal Due to the time required for ma ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Muscle preservation during weight loss in older, overweight individuals

    SBC: Essential Blends, LLC            Topic: N

    DESCRIPTION provided by applicant The overall goal of this project is to test a meal replacement beverage that will ultimately preserve muscle loss during calorie restriction weight loss CRWL in obese older individuals We previously developed a meal replacement rich with a proprietary blend of essential amino acids TMR that was more than three times as effective as whey protein in stimulat ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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