Award Data

The aim of this proposal is to develop an advanced blood simulant to replace current simulants used in combat medical training. A successful blood simulant will exhibit a caking/clotting response in the presence of simulated hemostatic agents while accur

An operational optical particle counter will be built, extensively characterized and evaluated that measures the size and shape of aerosol particles with optical diameter from 0.1 to 10 μm. This instrument will distinguish different species of dust and volcanic ash from other types of aerosol particles, and provide an estimate of the aerosol optical properties and produce compositional informati ...

The proposed effort covers the engineering aspects of a magnetic field source to be used in a table-top demonstrator of magnetic refrigeration. A prototype magnetic field source, based on the Halbach or "magic-ring" concept, will be designed, constructed and tested in the Phase I effort. The proposed device is based on an innovative concept that is simpler than current magic-ring configurations. ...

Major organ injuries such as liver, kidney, heart and lung injuries can lead to high morbidity and mortality in critically ill patients. Advanced noninvasive testing with high sensitivity and specificity is needed to detect specific organ injury particularly at early stages. Current techniques such as PCR, MS, absorption-based assays, ELISA and microfluidic-Luminex, cannot meet such requirements. ...

In this project, Parabon NanoLabs (PNL) will demonstrate the feasibility of extending its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce Essemblix-V, a platform for creating artificial vaccines from a predefined set of"building block molecules"assembled on DNA origami. Given an epitope for a potential ...

In this project, Parabon NanoLabs will employ its Essemblix(tm) Drug Development Platform, a combination of computer-aided design (CAD) software and DNA nano-fabrication technology, to produce artificial vaccines against the biothreat agent ricin on DNA origami decorated first with natural epitopes and ultimately with artificial epitotopes (hereafter"mimotope") constructed from a predefined set of ...

THE ADMINISTRATION HAS SET FORTH AN AMBITIOUS AGENDA IN "GOALS 2000" TO IMPROVE EDUCATION WITHIN OUR NATION. PRINCIPLES FROM QUALITY MANAGEMENT CAN PLAY A STRATEGIC ROLE IN HELPING US MEET THESE EDUCATION OBJECTIVES. BY EMPHASIZING THE STUDENT AS THE CUSTOMER AND KNOWLEDGE AS THE PRODUCT BEING DELIVERED, RESEARCH DEVELOPMENT CORPORATION (RDC) PROPOSES A METHODOLOGY FOR IMPROVING EDUCATION, PARTICU ...

As System-of-Systems (SoS) become more complex, interactions and latent emergent behaviors become difficult to identify and control. Unmanned Autonomous Systems (UAS) are a prime example of SoS that are both critical and difficult to assure. Drawing upon prior work into multi-criteria decision making (MCDM), DeVivo AST has developed TOP Score, a software tool that facilitates the modeling and anal ...

The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

RoadNarrows proposes a novel architecture to be implemented in a 6DOF vision system with applications in autonomous robotics. The system will report objects of interest along with location and pose information to a supervising computer. This system will be built around an advanced 3D vision platform that can deliver multiple video streams and 3D spatial measurements. The sensors will deliver high- ...