Award Data

Protection of deployed ground forces from disease-carrying insects requires the immediate and safe use of insecticides. Currently, control products are too slow to manage target pests and are unrealistic solutions under battlefield conditions. Vector-borne diseases transmitted by insects, such as malaria, dengue and leishmaniasis, are increasing worldwide and are more of a threat to our military f ...

ChromoLogic LLC (CL) is developing a Spectroscopic System for Therapeutic Drug Monitoring (THERASPEC), to meet the Armys need for a compact, robust system to assess the peak and trough therapeutic drug concentrations in blood to provide real-time TDM in fixed and field medical facilities. The THERASPEC prototype is based on spectroscopic

Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

including validation of cell extraction using standard assays and methods, and determination of the performance metrics. In addition, POC will develop a technology transition plan, FDA approval strategy, and a manufacturing plan for Phase III implementation.

Typical handheld medical ultrasound array probes are not well suited to point of injury care or attended casualty evacuation vehicles due to their bulky size and the requirement that the device be held in the hand of the medic. Portable ultrasound systems are available that allow for improved mobility, but a truly wearable portable system has not yet been realized. This proposal seeks to develop a ...

Problem: While most people fully recover from an m-TBI episode; 5-15% report cognitive symptoms after one year. 1 The residual symptoms commonly include impairments in memory, attention, reasoning, processing speed and executive functions. Providing effective telehealth solutions for this widely dispersed population would be lower cost than brick and mortar services. Opportunity: Mobile digital de ...

Musculoskeletal injury among military personnel is an under-recognized problem where shoulder injuries are significant and result in inflammation and pain from overuse, joint derangement, sprain/stain/rupture, and dislocation. Health hazard assessment is essential to ensure that fielded equipment and occupational duties do not exceed human capabilities over short and long term exposures. Hazard ...

The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

The vast majority of injuries in recent military conflicts have been inflicted by improvised explosive devices (IEDs) causing brain, extremities and genital-urinary injuries. Advanced computational models of IED blast physics and human body injury biomech

Military personnel must be protected from diseases transmitted by ticks and fleas, including Lyme disease. Effective surveillance of tick and flea vectors is vital to determine the population present, whether they are carrying disease, and whether control campaigns are working. Unfortunately, current surveillance tools are ineffective. In Phase I TDA designed, prototyped, and tested a novel ti ...