Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. 1. Drug-Eluting Bioresorbable Polymer Scaffolding for Treatment of Aortic Aneurys

    SBC: MEDSHAPE, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): This proposal is focused on the development of a bioabsorbable polymeric scaffold intended to provide both time-release delivery of therapeutic agents as well as structural support in the treatment of aortic aneurysms.An abdominal aortic aneurysm (AAA) is a condition in which the aorta, the main blood vessel in the abdomen, expands like a balloon. The aneurysm ...

    SBIR Phase II 2011 Department of Health and Human Services
  2. A Biomimetic Prehensile Digit for Upper-Limb Prostheses

    SBC: Invisible Hand Enterprises, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): Among amputation types involving the upper limbs, partial hand is the most prevalent by far and among the most challenging for prosthetists to address well. Sound side overreliance for these amputees gives rise to a high prevalence of contralateral overuse syndrome (COS), a progressive, painful, and debilitating condition. Research shows that prostheses reduce ...

    SBIR Phase I 2011 Department of Health and Human Services
  3. A Cell-based Assay for Botulinum Neurotoxin Detection and Development

    SBC: Q-Track Corporation            Topic: NIEHS

    DESCRIPTION (provided by applicant): The proposed effort aims to dramatically enhance the realism of radiation safety training for Emergency Responders, both First Responders, as well as Skilled Support Personnel. The goal is to develop andevaluate realistic dosimetry simulation or Dosimulation tools. These Realistic, Accurate Dosimulation (RAD) tools will be the centerpiece for ...

    SBIR Phase I 2013 Department of Health and Human Services
  4. A Compact, Portable Oxygen Generator

    SBC: TDA Research, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): In this Phase I SBIR project, TDA Research, Inc. will develop a compact, lightweight portable oxygen concentrator (POC) for medical operations and carry out a breadboard demonstration to produce continuous flow of enriched oxygen (O2) from ambient air. The new POC will weigh less than 10 lbs including the rechargeable batteries that will provide a minimum of 10 ...

    SBIR Phase I 2011 Department of Health and Human Services
  5. A Diarylheptanoid Scaffold to Treat Taopathies

    SBC: CFD Research Corporation            Topic: NIGMS

    DESCRIPTION: Pulmonary drug delivery is increasingly used for both treatment of lung diseases (such as asthma and chronic obstructive pulmonary disease) and in delivering drugs to the systemic circulation. To reach the desired effectiveness and safety oforally/nasally inhaled drugs, appropriate deposition of drugs on targeted region is essential. Due to complex pharmaceutical and physiological fa ...

    SBIR Phase I 2013 Department of Health and Human Services
  6. A Dietary Supplement As Adjunct Therapy In Castration-Resistant Prostate Cancer

    SBC: MetCure Therapeutics LLC            Topic: 102

    DESCRIPTION provided by applicant Castration Resistant Prostate Cancer Castration resistant prostate cancer CRPC directly contributes to patient mortality It is imperative to develop new and effective adjunct therapy to enhance the response of CRPC to hormonal therapy Recently we developed ProFineTM a proprietary formula consisting of bioactive flavonoids enriched in pomegranate fruit and ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. A Holographic Module for Multiphoton Microscopes in Neuroscience

    SBC: Boulder Nonlinear Systems, Inc.            Topic: 101

    DESCRIPTION provided by applicant Improving our understanding of the functional circuitry of the brain has important and manifold implications for our understanding of mental health as well as fields like consciousness and computing In the last decade optical techniques have arisen that allow both recording and control of targeted neurons for brain mapping and many of the best of these tech ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. A Neck Injury Assessment Tool

    SBC: CFD Research Corporation            Topic: DHP13009

    The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

    SBIR Phase II 2015 Department of DefenseDefense Health Program
  9. A next-generation spatial light modulator for mapping of neural networks

    SBC: Boulder Nonlinear Systems, Inc.            Topic: NIBIB

    DESCRIPTION provided by applicant Improving our understanding of the fundamental circuitry and dynamics of the brain has far reaching implications for a wide range of fields including mental health computing and the philosophy of the mind To this end one of the critical questions currently facing neuroscientists lies in how brain states and behaviors arise from the activity of ensembles of ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. A novel biomarker of infection in neutropenic cancer patients

    SBC: BIOPOWERTECH            Topic: NIAID

    DESCRIPTION provided by applicant Early diagnosis of an infection in neutropenic cancer patients is critical for timely treatment But the diagnosis of an infection in these patients especially at an early stage can be very challenging Therefore there is a great need for sensitive biomarkers that can rapidly predict an infection and provide possible outcomes We have already reported that s ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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