Award Data

Current methods for stem cell isolation are time-consuming, costly, and labor-intensive, and ill-suited for point of care applications. To overcome these limitations, we propose to develop and demonstrate a high-throughput, non-invasive, microfluidic stem cell analyzer to enable a rapid isolation of high-quality stem cell products from clinically relevant samples. Our technology enables significan ...

Musculoskeletal injury among military personnel is an under-recognized problem where shoulder injuries are significant and result in inflammation and pain from overuse, joint derangement, sprain/stain/rupture, and dislocation. Health hazard assessment is essential to ensure that fielded equipment and occupational duties do not exceed human capabilities over short and long term exposures. Hazard ...

The overall objective of the proposed project is to develop new injury criteria, model based risk assessment methodology, and a software tool to assess neck injury risk from head supported mass (HSM) loading. Based on the foundation of Phase I feasibility studies, the proposed Phase II work will focus on model enhancement, extension and validation, risk assessment, and software integration and tes ...

The vast majority of injuries in recent military conflicts have been inflicted by improvised explosive devices (IEDs) causing brain, extremities and genital-urinary injuries. Advanced computational models of IED blast physics and human body injury biomech

Magnetic resonance imaging (MRI) has become a primary diagnostic tool in scientific research and clinical imaging. Despite the excellent image quality that can be obtained with today’s MRIs, images acquired using different MRI systems and during longitudinal studies are not reproducible, and hence can be difficult, if not impossible, to compare. To address this issue, a standardized test of the ...

The broader impact/commercial potential of this project includes peak demand relief for utilities, reduced freezer operating costs for retail stores, and natural refrigerants for regulators. Unfortunately, no state-ofthe- art system simultaneously addresses all these issues. Industrial/commercial batteries remain unaffordable, refrigeration costs account for 60% of a retail store?s electricity bil ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be to increase the efficiency of domestic oil production. Using current methods, the oil industry is able to extract only 5% of the known hydrocarbon from shale formation. This represents more than $500B of potential oil and gas that cannot be economically produced for the US economy. Th ...

The broader impact/commercial potential of this Small Business Innovation Research Phase II project is that the palladium on hierarchically porous monolithic carbon catalyst being developed promises longer lifetimes and higher performance to industrial chemical companies. This more active, more selective catalyst can lower the operating temperature in chemical reactions thereby decreasing energy u ...

The broader impact/commercial impact of this Small Business Innovation Research (SBIR) Phase II project is in promoting the protection of human health, the environment, and our nation's natural resources by providing new sensors that enable fast, accurate, cost-effective sampling and analysis tools to monitor pollution and exposure. The innovations developed here will allow for the rapid identific ...

This SBIR Phase II project studies the problem of how to engage students in STEM (Science Technology Engineering and Mathematics) education through game-based learning in a Virtual Robotics computer game. In the game, students design, assemble and train virtual walking robots to compete against their peer robots to secure a seat on a virtual mission to Mars. The project analyses the effects of com ...